Kidney Structure and Function Flashcards

1
Q

kidneys

A

excretory organs that process and filter the blood and rid the body of metabolic waste via urine

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2
Q

hilum

A

point at kidneys where many structures e.g arteries, veins etc enter and leave

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3
Q

what are the kidneys encased in

A

renal fat pad

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4
Q

what are the 3 distinct parts of the kidneys

A

cortex (contains 85% of nephrons)
medulla - triangles
pelvis (where urine is collected)

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5
Q

describe the pathway of blood through the kidneys starting with the abdominal aorta and ending at the interlobular veins

A

abdominal aorta - renal artery - interlobular arteries - afferent arteriole - glomerular capillary - efferent arteriole - peritubular capillaries - interlobular veins

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6
Q

what makes kidney vascalature unique

A

they have 2 lots of capillaries

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7
Q

cortical nephron

A

majority, short loop of henle, located in the kidney cortex

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8
Q

juxtamedullary nephron

A

long loops of henle, near medulla, specialised for water absorption

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9
Q

describe the pathway of the filtrate as it moves through the kidney

A

glomerulus - bowmans capsule - proximal convuluted tubule - loop of henle - distal convoluted tubule - collecting duct

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10
Q

what does the renal corpuscle consist of and what is its function

A

glomerulus and bowmans capsule

filtration and removal

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11
Q

what does the renal tubule consist of and what is its function

A

prox conv tubule, loop of henle, dist conv tubule

resorption, secretion (fine tuning)

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12
Q

glomerulus

A

network of capillaries that filters the blood

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13
Q

bowmans capsule

A

double layered structure that surrounds the glomerulus and collects filtrate

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14
Q

layers of bowmans capsule

A

outer layer - parietal
inner layer - visceral - made up of podocytes which have long processes called pedicels which wrap around glomerular capillaries

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15
Q

hydrostatic pressure in the glomerulus

A

afferent arteriole wider than efferent meaning molecules and fluid are pushed through the filtration barrier

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16
Q

what cant pass through the filtration barrier

A

cells
large proteins e.g haemoglobin
-ve charge proteins

17
Q

what is glomerular hydrostatic pressure counteracted by

A

hydrostatic pressure in bowmans capsule

glomerular osmotic pressure (proteins in glomerulus want to hold onto water)

18
Q

GFR

A

glomerular filtration rate

19
Q

what does a reduced GFR result in

A

accumulation of waste in the blood

insufficient blood clearance and waste removal

20
Q

how is the GFR estimated

A

serum creatinine test