Kidney Physiology 2nd lecture (nephrons specific) Flashcards
What does nephron loop do?
Helps us concentrate filtrate
Where we start the mechanism to concentrate urine
What does descending limb of nephron loop do?
Reabsorb water
What does ascending limb of nephron loop do?
Reabsorb sodium
Reabsorb chlorine
Reabsorb potassium
Secretion of urea
What does the loop of Henle do?
Absolutely nothing
No substances move in or out of this shit
When dehydrated, water is __ by producing very ___ urine
Conserved
Concentrated
When overhydrated, excess water is __ producing very __ urine
Released
Dilute
Kidneys create and maintain an osmotic gradiant using what?
Counter current multiplyer
Countercurrent exchanger
The collecting ducts of all nephrons use osmotic gradient for what?
To adjust the filtrate water volume
What does the countercurrent multiplier do?
Makes a gradient of low solute concentration at the renal cortex to a high solution concentration at the deepest part of renal medulla
Vasa recta
Reabsorbs water into general circulation without undoing the osmotic gradient
What happens at distal convoluted tubule?
Reabsorption of sodium
Reabsorption of clorine
Reabsorption of calcium
Secretion of potassium
What hormone allows for the reabsorption of soidium and clorine in distal convoluted tubule?
Aldosterone
What hormone allows for reabsorption of calcium in distal convoluted tubule?
Parathyroid hormone
What hormone allows for secretion of potassium in DCT?
Aldosterone
What does collecting duct do?
Reabsorbs Sodium
Reabsorbs Clorine
Reabsorbs water
Secretes potassium
What hormone allows the reabsorption of water in collecting duct?
Antidiuretic
When you are overhydrated/ hydrated what happens?
There is more water, less sodium
Little antidiuretic hormone released
Water releases
Urine output is large and diluted
Blood pressure/ volume decreases
What happens when you’re dehydrated?
Less water, more sodium
More antidiuretic released
Water reabsorbed
Urine output small and concentrated
Blood volume/ pressure increases
What do diuretics do?
Stops release of antidiuretic hormone
What decreases permeability of collecting duct?
Diuretics
