Kidney Function Flashcards

1
Q

What is ultrafiltration?

A

The non-specific filtration of the blood under high pressure

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2
Q

Where does ultrafiltration occur?

A

In the Bowman’s capsule of the nephron

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3
Q

Where does the blood move into the kidneys through?

A

The afferent arterioles

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4
Q

What is the Bowman’s capsule comprised of?

A

An inner surface of cells called podocytes

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5
Q

What are pedicels?

A

Cellular extensions of podocytes that wrap around the blood vessels;s of the glomerulus

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6
Q

What is between podocytes and the glomerulus that filters the blood?

A

A glycoprotein matrix called the basement membrane

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7
Q

What is the sole filtration barrier within the nephron?

A

Basement membrane

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8
Q

What does the filtrate not contain?

A

Blood cells, platelets, and plasma proteins

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9
Q

What is selective reabsorption?

A

the reuptake of useful substances from the filtrate

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10
Q

Where does selective reabsorption occur?

A

occurs in the convoluted tubules

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11
Q

Where does The majority of selective reabsorption occur in?

A

Proximal convoluted tubule

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12
Q

What are some reabsorbed substances?

A

Water, salts, glucose, and amino acids

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13
Q

What are the several adaptive features of the proximal convoluted tubule?

A

Microvilli, co-transporter proteins, many mitochondria, tight junctions

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14
Q

How are Na+ ions transported from the proximal convoluted tubule into the surrounding tissues?

A

Active transport

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15
Q

What does the electrical gradient caused by t6he positively charged sodium ions cause?

A

Chloride ions to follow by diffusion

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16
Q

What happens in selective reabsorption after chloride ions are diffused?

A

Sugars and amino acids are transported into the surrounding tissues by co-transporter proteins

17
Q

What does the movement of ions, sugars, and amino acids into the surrounding tissues cause?

A

An increase in the osmolarity of the tissues

18
Q

What does an increase of osmolarity in the tissue cause?

A

Water leaves the proximal convoluted tubule by osmosis

19
Q

Where does osmoregulation occur?

A

Occurs in the medulla

20
Q

What is the function of the loop of Henle?

A

establishes a salt gradient (hypertonicity) in the medulla

21
Q

What does the anti diuretic hormone regulate?

A

The level of water reabsorption in the collecting duct?

22
Q

How does the loop of henle ensure that the production of urine that is more concentrated than the blood

A

countercurrent multiplier system

23
Q

What increases as the descending limb moves down into the medulla

A

The osmolarity of the filtrate

24
Q

Why is the descending limb low-permeable to ions?

A

Has few transport proteins in the membrane of its cells

25
Q

What is unable to permeate the ascending limb of the loop of Henle?

A

Water

26
Q

What is the capillary that flows directly alongside the loop of Henle

A

Vasa recta

27
Q

What is the role of the vasa recta?

A

supplies oxygen to and removes carbon dioxide from the respiring cells of the loop of Henle