Kidney Disorders Flashcards
Hardening of renal arteries
Nephrosclerosis
Causes of Nephrosclerosis
-Prolonged Hypertension
-Diabetes
Seen commonly in older adults and is associated with atherosclerosis and hypertension
Benign neprhosclerosis
Usually occurs in young adults and is often associated with significant HTN (DBP <130)
Malignant nephrosclerosis
Clinical Manifestations of Nephrosclerosis
-Rare early in disease
- (+) proteinuria
- (+) casts in urine
Later manifestations:
-Renal insufficiency manifestations
Medical Management of Nephrosclerosis
-Aggresive antihypertensive therapy
(ACE Inhibitors, alone or in combination with other antihypertensive)
Is a genetic disorder characterized by the growth of numerous fluid-filled cysts in the kidneys, which destroy the nephrons?
Polycystic kidney disease (PKD)
Two forms of PKD
Autosomal dominant & Autosomal Recessive
Most common symptoms appear between 30-40 years of age
Autosomal dominant
Rare form and symptoms begin in the earliest months of life or in the utero
Autosomal recessive
Clinical Manifestations of PKD
-Hematuria
-Polyuria
- Hypertension
- Kidney stones
- Proteinuria
- Abdominal fullness
- Flank pain
Diagnostics for PKD
UTZ of kidneys
A preferred technique for diagnosis
UTZ of kidneys
Medical Management of PKD
-No cure
- Supportive
-BP control
-Pain control
- Antibiotics for infections
- Renal Replacement, if with kidney failure
It is a type of acute glomerulonephritis
Acute Post Streptococcal Glomerulonephritis
Common among children and young adults, but can affect all age groups
Acute Post Streptococcal Glomerulonephritis
Develops 5 to 21 days after an infection of tonsils, pharynx, or skin by GABHS
Acute Post Streptococcal Glomerulonephritis
Clinical Manifestations of Acute Post Streptococcal Glomerulonephritis
-Hematuria (microscopic or macroscopic)
-Urine may appear as tea-or cola- colored
-Edema
-Azotemia
- Proteinuria
- Hypertension
Abnormal concentration of nitrogenous wastes in blood
Azotemia
APSGN Diagnostics
-Anti-streptolysin O (ASO Titer)
-Urinalysis
- BUN
-Creatinine
Determines the presence of immune response to strep
ASO Titer
Reveals the presence of hematuria
Urinalysis
Prognosis of APSGN
->95% recover completely
-5% to 15% develops chronic glomerulonephritis
-1% develops irreversible renal failure
Medical Management of APSGN
-Bed rest until s/sx of glomerular inflammation and HTN subside
-Diet: low protein, low sodium, fluid restricted
-Antibiotics, only if strep infection is present
Nursing Management of APSGN
-Early detection and prompt treatment of sore throats and skin lesion
- Encourage to take full course of antibiotic
- Encourage good personal hygiene
- Instruct to comply with prescribe diet and fluid restriction
Is a type of kidney disease characterized by increased glomerular permeability and is manifested by massive proteinuria
Nephrotic Syndrome
Nephrotic Syndrome Clinical Manifestations
-Edema
-Massive proteinuria
- Hypertension
- Hyperlipidemia
- Hypoalbuminemia
Nephrotic Syndrome Complications
-Infection
- Thromboembolism (Most commonly affects renal vein)
- Pulmonary embolism
-Acute kidney injury
-Accelerated atherosclerosis
Nephrotic Syndrome Medical Management (Goals)
-Treat underlying cause
-Slow progression of CKD
- Symptomatic relief
Nephrotic Syndrome Medical Management
-Diuretics, as ordered
-ACE inhibitors (to reduce proteinuria)
-Lipid (Lowering agents for hyperlipidemia)
Refers to the stone
Calculus
Refers to stone formation
Lithiasis
More common among men, except for struvite stones
Urinary Tract Calculi
Types of kidney stones
-Calcium stone
- Uric acid stone
- Struvite stone
- Cysteine stone
Small, often possible to get trapped in the ureter
Calcium oxalate stones