Kidney as Producer, Excreter and Regulator Flashcards

1
Q

Why are you likely to get anaemia with CKD

A

Erythropoietin released from peritubular cells in kidney

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2
Q

What does erythropoietin stimulate?

A

Production of pro erythroblasts (pronormoblast) that will then differentiate to become reticulocyte (polychromatic erythrocyte) in bone marrow
Polychromatic erythrocyte will mature to erythrocyte within blood

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3
Q

Tight junctions

A

Fusion of adjacent cell membranes to create a barrier to passage of water and dissolved particles

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4
Q

Filtration fraction

A

Glomerular filtration flow over renal plasma flow- shows portion of fluid reaching kidneys, being filtered

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