Kidney And Systemic Disease Flashcards
What is Diabetic Nephropathy?
The decline in GFR rate until reaching failure with rise of BP and CV risk
Logically, what would the risk factors for diabetic nephropathy be?
Hypertension, smoking, long standing hyperglycemia
What are the two stages of diabetic nephropathy?
Hypertrophy Hyperfunction? And then nephropathy.
Diagnosis of diabetic nephropathy?
Proteinurea, diabetic retinopathy
How to prevent diabetic nephropathy!
No smoking, control BP and sugars and exercise and what not
Treatment goals for Diabetic nephropathy?
Lower blood sugar, BP, and reduce glomerular capillary pressure
What do we give for diabetic nephropathy patients with albuminurea and hypertension?
Renin angiotensin inhibition (RAS)
What do we give for diabetic nephropathy patients with type 2 and CKD?
SGLT2i
What is Lupus nephritis caused by?
SLE forms immune complexes that depose in the kidneys
What immune complex is deposited into the glomeruli?
Ag AB immune complexes
What negative do the immune complexes do to the kidneys?
They promote an inflammatory response.
Signs of Lupus nephritis then??
AKI, nephrotic syndrome, hematuria, proteinurea
What’s the classification method used for lupus nephritis then?
ISNRPS
Explain the ISNRPS?
class 1 is minimal, class 6 is advanced sclerosing lupus nephritis
How do we make sure that Lupus is present?
Renal biopsy
