Electrolyte Disorders 1 Flashcards
Total body water is mainly regulated by?
Hypothalamic osmoreceptors
Vasopressin release into the circulation is regulated by?
Serum tonicity
What increases Vasopressin secretion?
Extracellular fluid volume depletion or hypotension
Vasopressin interacts with the 3 receptors….?
V1a, V1b, and V2
The 3 receptors active Cyclic AMP, what’s the effect of this interaction?
Increases water permeability of the collecting duct
What is Hyponatremia?
Decreased serum sodium
What causes Hyponatremia?
Excessive water ingestion
Treatment of Hyponatremia?
Fluid restriction and loop diuretics
How do we treat Hyponatremia if accompanied by mental status change?
Saline administration
Causes of hypernatremia?
Surgery involving pituitary, excess water loss, diabetes insipidus
How do we treat mild hypernatremia?
Fluid replacement
How do we treat more severe cases of hypernatremia?
IV glucose 5%
