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FEK Y2 > Kidney and Bladder Neoplasm > Flashcards

Kidney and Bladder Neoplasm Flashcards

1
Q

“fall foliage” kidney tumor

A

renal adenocarcinoma appearance - due to vascularity and hemorrhage in the neoplasm

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2
Q

most common type of kidney tumor

A

renal adenocarcinoma

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3
Q

four types of renal adenocarcinoma

A
  1. clear cell carcinoma 2. granular cell carcinoma 3. papillary tumors 4. sarcomatoid tumors
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4
Q

what is this?

A

clear cell carcinoma, kidney

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5
Q

describe granular cell carcinoma

A

eosinophilic cytoplasm w/ granular texture (b/c lots of mitochondria and other cytoplasmic organelles)

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6
Q

what is this?

A

papillary adenocarcinoma

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7
Q

what is this?

A

sarcomatoid carcinoma

spindle cell morphology

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8
Q

Nephroblastoma/Wilm’s tumor - who gets it?

Prognosis?

A

common in children 2-4yrs

prognosis = favorable. anaplastic histology = bad. worse prognosis for older children

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9
Q

pathology of nephroblastoma/Wilm’s tumor

A

large w/ fleshy, lobulated appearance - palpated on PE

undifferentiated cells

anaplastic Wilm’s: atypical nuclei w/ prominent nucleoli and mitotic activity = worse prognosis

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10
Q

what is this

A

stromal cells in nephroblastoma

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11
Q

schistosomiasis causes what type of neoplasm?

A

transitional cell carcinoma of the bladder

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12
Q

field change concept

A

type or degree of histological change in the urothelium adjacent to or remote from a clinically detected tumor

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13
Q

renal cell carcinoma presentation

A

hematuria, pain, flank mass

systemic signs (fever, anemia, hepatic dysfunction, amyloidosis)

paraneoplastic syndromes

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14
Q

best predictor of renal cell carcinoma

A

stage (metastasis?)

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15
Q

natural hx of renal cell carcinoma

A

unpredictable

spontaneous regression (rare)

common locations of metastatic spread: lungs, bones

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16
Q

what is this?

A

Wilm’s tumor / nephroblastoma

17
Q

urothelial transitional cell tumors - multiplicity and multicentricity

A

common for multiple tumors to pop up at the same or different time, in the same place or elsewhere in the tract b/c urothelium undergoes field change

18
Q

what is the major risk factor for bladder cancer ?

A

smoking

19
Q

how to dx bladder cancer?

histologic appearance

A

cytology, cystoscopy w/ biopsy

appearance: papillary like brocoli heads

20
Q

what is this?

A

bladder cancer

21
Q

what is this?

A

urothelial carcinoma-in-situ

no maturation from BM to top

22
Q

upper urothelial tract cancer

A

not as common as renal cell carcinoma

epi: elderly, more common in males
presentation: hematuria

FEK Y2 (17 decks)

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