Khanim - Nuclear Receptors

Question 1

State the three broad classes of nuclear receptors

Answer 1

• Classic Steroid receptors
• Adopted Orphan Receptors
• Orphan receptors

Question 2

Give an example of a classic Steroid nuclear receptor

Answer 2

Glucocorticoid receptor

Question 3

Give an example of an Adopted Orphan receptor

Answer 3

The PPAR receptors

Question 4

What are “nuclear receptors”?

Answer 4

Nuclear receptors are a superfamily of structurally conserved, ligand dependent transcription factors which regulate gene expression.