Keywords - gene expresssion Flashcards
acetylation
process by which acetyl group (from acetyl coenzyme A) is added to a histone - removal is deacetylation
chromatin
material that makes up chromosomes, consists of DNA and histone proteins
epigenetics
where environmental factors cause heritable changes in gene function w/o changing the base sequence of DNA
gene mutation
change to one or more nucleotide bases in DNA, resulting in a change in the genotype which may be inherited
genome
complete map of all genes on the individual chromosomes of an organism
methylation
addition of a methyl group (CH3) to cytosine bases of DNA, which inhibits transcription of genes
oncogene
mutation of a proto-oncogene, causing cells to divide too rapidly and out of control
proteome
all the proteins produced in a given type of cell or organism at a given time, under specific conditions
totipotency
ability of a single cell to divide and differentiate into any type of cell
tumour suppressor gene
gene that maintains normal rates of cell division and so prevents development of tumours, repairs DNA mistakes + apoptosis