Key Terms- PHARM Flashcards
process by which drugs are transferred from the site of entry into the body to the bloodstream
Absorption
undesirable effects other than the intended therapeutic effect of a drug
Adverse drug reactions
immune system response that occurs when the body interprets an administered drug as a foreign substance and forms antibodies against the drug
Allergic effect
glass flask containing a single dose of medication for parenteral administration
Ampule
severe reaction occurring immediately after exposure to a drug; characterized by respiratory distress and vascular collapse
Anaphylactic reaction/Anaphylaxis
The portion of a drug that reaches the systemic circulation and can act on the cells is called the drug’s ____________.
Bioavailability
movement of drugs by the circulatory system to the site of action
Distribution
tendency of the body to become accustomed to a drug over time; larger doses are required to produce the desired effects
Drug tolerance
study of the effect of ethnicity on responses to prescribed medication, especially drug absorption, metabolism, distribution, and excretion
Ethnopharmacology
removal of a drug from the body
Excretion
name assigned by the manufacturer who first develops a drug; it is often derived from the chemical name
Generic name
the amount of time it takes for half a dose of a drug to be eliminated from the body
Half-life
unusual, unexpected response to a drug that may manifest itself by overresponse, underresponse, or response different from the expected outcome
Idiosyncratic effect
(1) act of breathing in; synonym for inspiration; (2) administration of a drug in solution via the respiratory tract
Inhalation
injection placed just below the epidermis
Intradermal injection
an injection into deep muscle tissue, usually of the buttock, thigh, or upper arm
Intramuscular (IM) injection
injection of a solution into the vein
Intravenous (IV) route
process of creating an accurate list of all medications a patient is taking, including drug name, dosage, frequency, and route, and comparing the list to the physician’s admission, transfer, or discharge orders, with the goal of providing correct medications to the patient at all transition points within the hospital
Medication reconciliation
(1) chemical changes in the body by which energy is provided; (2) breakdown of a drug to an inactive form; also referred to as biotransformation
Metabolism
popularly used to refer to injection routes
Parenteral
highest plasma concentration of a drug
Peak level
process by which drugs alter cell physiology and affect the body
Pharmacodynamics
the study of how genetic variation affects an individual’s response to drugs
Pharmacogenetics
use of information about a person’s genetic makeup, or genome, to choose the drugs and drug doses that are likely to work best for that person
Pharmacogenomics
movement of drug molecules in the body in relation to the drug’s absorption, distribution, metabolism, and excretion
Pharmacokinetics
study of actions of chemicals on living organisms
Pharmacology
dynamic that achieves the desired therapeutic effect of the drug without causing other undesirable effects
Pharmacotherapeutics
intermittent IV administration of medications through a primary IV line, with the additive container positioned higher than the primary IV solution
Piggyback infusion