Key Points from KT

Question 1

Mitochondrial Inheritance

Answer 1

only females can transfer the mt mutation to their offspring
heteroplasty often results in incomplete penetrance
mt disease are classified by type of mutations causing them
this has roles in DM, aging , and alziemhers

Question 2

x linked recessive

Answer 2

from an unaffected carrier female to male

in these pedigrees we will see carrier females and affected males

Question 3

x linked dominant

Answer 3

50% of sons affected, 50% of daughters affected
vertical tranmission
2:1 females to males affected
father to son transmission is NOT seen

Question 4

HGP: Human Genome Project

Answer 4

a catalog of human genes

Question 5

meiosis

Answer 5

dealing with gametes
you will see homolog exchange of material (which I s different between meiosis and mitosis)
1 diploid to 4 haploid gametes

Question 6

mitosis

Answer 6

we have 1 diploid and we get 2 daughter cells
here we see no pairing of homologs and no exchange of material

this process takes roughly 1- 2 hours and the end result is that

Question 7

DNA replication

Answer 7

happens during interphase
part of the central dogma
end goal is producing 2 identical copies of DNA

Question 8

Transcription

Answer 8

this is when DNA becomes RNA

this involves a silencer, enhancer, coactivator

Question 9

Translation

Answer 9

mRNA -> protein … Ribosomes perform and RNA brings AA for assembly

Question 10

what are some factors the regulate gene expression