Final Questions Flashcards
chromosome disorders
Entire chromosomes (or large segments of them) are missing, duplicated, or otherwise altered.
example of chromosome disorders
Down syndrome and Turner syndrome
single gene disorders
Disorders in which single genes are altered; these are often termed mendelian conditions
examples of single gene disorders
cystic fibrosis, sickle cell disease, and hemophilia
multifactorial disorders
Result from a combination of multiple genetic and environmental causes
examples of multifactorial disorders
cleft lip and cleft palate, as well as many adult disorders, including heart disease and diabetes
mitochondrial disorders
Relatively small number of diseases caused by alterations in the small cytoplasmic mitochondrial chromosome
how are single gene disorders classified
based on how they are inherited
- Autosomal dominant
- Autosomal Recessive
- X-Linked
Achondroplasia has a high mutation rate. This is most likely the result of
Methylated CG dinucleotide
chromatin
Substance that gives the nucleus a granular appearance, is observable in the nuclei of nondividing cells
chromosomes
chromosomes contain genes
what does A
T
What does G match with
C
what is an allele
version or forms of a gene in a population
what is a locus
genes location on a chromosome
