key cancer translocations Flashcards

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1
Q

8;14

A

burkitt > 8/myc on 14/Ig

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2
Q

14;18

A

follicular > 18/bcl on 14/Ig

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3
Q

11;14

A

mantle > 11/cyclin D on 14/Ig

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4
Q

9;22

A

CML > bcr-abl > tx. w/Imatinab - TKI

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5
Q

15;17

A

AML > mutant RA-R blocking WBC differentiation

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