Key Associations Flashcards
Associated with
Actinic (solar) keratosis
Precursor to Squamous Cell Carcinoma
Associated with
Acute gastric ulcer associated w/ CNS injury
Cushing’s ulcer
High ICP –> Vagal gastric secretion
Associated with
Acute gastric ulcer associated w/ severe burns
Cushing’s ulcer
Reduced plasma volume–>Sloughing of gastric mucosa
Associated with
Alternating areas of transmural inflammation and normal colon
Skip lesions (Crohn’s disease)
Associated with
Aneurysm, dissecting
Hypertension
Associated with
Aortic aneurysm: Abdominal and Descending aorta
Atherosclerosis
Associated with
Aortic aneurysm: Arch
Tertiary syphillis (syphilitic aortitis) -->Vaso vasorum destruction
Associated with
Aortic aneurysm: Ascending
Marfan’s Syndrome (idiopathic cystic medial degeneration)
Associated with
Atrophy of the mamillary bodies
Wernicke’s encephalopathy
Thiamine deficiency–>Ataxia, opthalmoplegia, confusion
Associated with
Autosplenectomy (Fibrosis & Shrinkage)
Sickle cell anemia (Hemoglobin S)
Associated with
Bacteria associated w/ gastritis, peptic ulcer disease, and stomach cancer
H.pylori
Associated with
Bacterial meningitis (Adults and Elderly)
Strep Pneumoniae
Associated with
Bacterial menigitis (Newborns and Kids)
Group B Strep (Newborns)
S. pneumoniae/Neisseria meningitidis (kids)
Associated with
Benign melanocytic nevus
Spitz nevus (Most common in first two decades)
Associated with
Bleeding disorder w/ GpIb deficiency
Bernard-Soulier syndrome
Defect in platelet adhesion to von Willebrand factor
Associated with
Brain tumor (Adults)
Supratentorial:
Metastasis
> Astrocytoma (including Glioblastoma multiforme)
>Meningioma
>Schwannoma
Associated with
Brain tumor (Kids)
Infratentorial?
Supratentorial?
Infratentorial: Medulloblastoma (cerebellum)
Supratentorial: Craniopharyngioma (Cerebrum)
Associated with
Breast cancer
Infiltrating ductal carcinoma
In the U.S., 1 in 9 women will develop breast cancer
Associated with
Breast mass (benign)
Fibroadenoma
Associated with
Cardiac primary tumor (Kids)
Rhabdomyoma
Often seen in Tuberous sclerosis
Associated with
Cardiac manifestation of lupus
Libman-Sacks endocarditis
NON-bacterial, affecting BOTH SIDES of MITRAL valve
Associated with
Cardiac tumor (adults)
Metastasis
Primary Myxoma
(4:1 L atrium to R atrium
“Ball & valve”)
Associated with
Cerebellar tonsillar herniation
Chiari malformation (Often presents w/ progressive HYDROCEPHALUS or SYRINGIOMYELIA)
Associated with
Chronic arrythmia
Atrial fibrillation (High risk of emboli)
Associated with
Chronic atrophic gastritis (autoimmune)
Predisposition to gastric cancer
Can cause Pernicious anemia
Associated with
Clear cell adenocarcinoma of the vagina
DES (Diethylstilbestrol) exposure in utero
Associated with
Compression fracture
Osteoporosis
Type I: Postmenopausal women
Type II: Elderly
Associated with
Congenital adrenal hyperplasia, hypotension
21-hydroxylase deficiency
Associated with
Congenital cardiac anamoly
VSD
Associated with
Congenital conjugated hyperbilirubinemia
“Black liver”
Dubin-Johnson syndrome
hepatocytes can’t secrete conjugated bilirubin into bile
Associated with
Constrictive pericarditis
Tuberculosis (developing world)
SLE (developed world)
Associated with
Coronary artery involved in thrombosis
LAD > RCA > LCA
Associated with
Cretinism (Severely stunted growth)
Iodine deficit/Hypothyroidism
Associated with
Cushing’s syndrome
Iatrogenic cushing’s = Corticosteroid therapy
Adrenocortical adenoma (secretes Cortisol)
ACTH-secreting pituitary adenoma
Paraneoplastic cushing’s (ACTH secretion by tumors)
Associated with
Cyanosis (early after birth; less common)
Tetralogy of Fallot (PROVe)
Transposition of great vessels
Truncus arteriosis
Associated with
Cyanosis (late after birth; more common)
VSD, ASD, PDA
Associated with
Death in CML
Blast crisis
Associated with
Death in SLE
Lupus nephropathy
Associated with
Dementia
Alzheimer’s disease
Multiple infarcts
Associated with
Demyelinating disease in young women
MS
Associated with
DIC
Severe sepsis Obstetric complications Cancer Burns Trauma Major surgery
Associated with
Dietary deficit
Iron
- ->MICROcytic, HYPOchromic anemia
- ->Plummer-Vinson syndrome
Associated with
Diverticulum in pharynx
Zenker’s diverticulum
Diagnosed by barium swallow
Associated with
Ejection click
Aurtic/pulmonic stenosis
Associated with
Esophageal cancer
Squamous cell carcinoma (Worldwide)
Adenocarcinoma (U.S.)
Associated with
Food poisoning (endotoxin-mediated)
S. Aureus
B. Cereus
Associated with
Glomerulonephritis (adults)
Berger’s disease (IgA nephropathy)
Associated with
Gynecologic malignancy
Endometrial carcinoma (U.S.)
Cervical carcinoma (Worldwide)
Associated with
Heart murmur, congenital
MITRAL valve prolapse
Associated with
Heart valve in bacterial endocarditis
Mitral
> Aortic (rheumatic fever)
> Tricuspid (IV drug abuse)
Associated with
Helminth infection (U.S.)
Enterobius vermicularis
Ascaris lumbricoides
Associated with
Hematoma: Epidural
Middle Meningeal Artery rupture
Lentiform/Banana
Lucid interval
Trauma
Associated with
Hematoma: Subdural
Bridging Veins rupture
Crescent
Associated with
Hemochromatosis
Multiple drug transfusions
Hereditary HFE mutation
Can result:
CHF
“Bronze diabetes”
HEPATOCELLULAR CARCINOMA
Associated with
Hereditary bleeding disorder
von Willebrand’s disease
Associated with
Hereditary harmless jaundice
Gilbert’s syndrome
Benign, unconjugated hyperbilirubinemia
Associated with
HLA-B27
Ankylosing spondylitis
Reiter’s syndrome
UC: Ulcerative colitis
Psoriasis
Associated with
HLA-DR3 or DR4
Diabetes mellitus Type 1
RA
SLE
Associated with
Holosystolic murmur
VSD
Tricuspid regurgitation
Mitral regurgitation
Associated with
Hypercoagulability
Endothelial damage
Blood stasis
Virchow’s triad (–>Venous thrombosis)
Associated with
HyPERtension, secondary
Renal disease
Associated with
HyPOparathyroidism
Accidental excision during thyroidectomy
Associated with
HyPOpituitarism
Pituitary adenoma (usually benign)
Associated with
Infection secondary to blood transfusion
Hepatitis C
Associated with
Infective agents in chronic granulomatous disease
Catalase + organisms:
Staph aureus
E. coli
Aspergillus
Associated with
Kidney stones
Calcium = radiOPAQUE
Struvite (Ammonium) = radiOPAQUE
formed by urease positive organisms
Proteus vulgaris
Staphylococcus
Uric acid = radioLUCENT
Associated with
Late cyanotic shunt
Uncorrected L–>R becomes R–>L
Eisenmenger’s syndrome
Cause by ASD, VSD, PDA
Results in:
PULMONARY HYPERTENSION &
POLYCYTHEMIA
Associated with
Liver disease
Alcoholic cirrhosis
Associated with
Lysosomal storage disease
Gaucher’s
Associated with
Male cancer
Prostatic carcinoma
Associated with
Malignancy associated w/ NONinfectious fever
Hodgkin’s lymphoma
Associated with
Malignancy (kids)
ALL
Medulloblastoma (cerebellum)
Associated with
Mental retardation
Down Syndrome
Fragile X
Associated with
Metastases from bone
Prostate, breast
> Lung
> Thyroid, testes
Associated with
Metastases from brain
Lung >Breast >Genitourinary >Osteosarcoma >Melanoma >GI
Associated with
Metastases from liver
Colon
» Stomach
> Pancreas
Associated with
Mitochondrial inheritance
Disease occurs in both males & females
Inherited through females only
Most mutations related to ETC
Associated with
Mitral valve stenosis
Rheumatic heart disease
Associated with
Mixed (UMN and LMN) motor neuron disease
ALS
Associated with
Myocarditis
Coxackie B
Associated with
Nephrotic syndrome (Adults)
Focal segmental sclerosis
Associated with
Nephrotic syndrome (Kids)
Minimal change disease
Associated with
Neuron migration failure
Kallmann syndrome
(HyPOgonadotropic hyPOgonadism
& anosmia (can’t smell)
Associated with
Nosocomial pneumonia
Klebsiella
E. coli
Pseudomonas aeruginosa
Associated with
Obstruction of male urinary tract
BPH
Associated with
Opening snap
Mitral stenosis
Associated with
Opportunistic infection in AIDS
Pneumocystis jirovecii
Associated with
Osteomyelitis
S. aureus
Associated with
Osteomyelitis in Sickle cell disease
Salmonella
Associated with
Osteomyelitis w/ IV drug use
Pseudomonas
S. Aureus
Associated with
Ovarian metastasis from gastric carcinoma or breast cancer
Krukenberg tumor
Mucin-secreting SIGNET-RING cells
Associated with
Ovarian tumor (benign, bilateral)
Serous cystadenoma
Associated with
Ovarian tumor (malignant)
Serous cystadenocarcinoma
Associated with
Pancreatitis (Acute)
Gallstones
Alcohol
Associated with
Pancreatitis (Chronic)
Alcohol (Adults)
Cystic Fibrosis (Kids)
Associated with
Patient demographic w:
ALL
CLL
AML
CML
ALL: Child
CLL: Adult >60
AML: Adult ~65
CML: Adult 30-60
Associated with
PID: Pelvic inflammatory disease
Chlamydia trachomatis
Neisseria gonorrhoeae
Associated with
Philadelphia chromosome (9;22) (brc-abl)
CML (Sometimes associated w/ ALL/AML)
Associated with
Pituitary tumor
Prolactinoma
(Somatotropic “acidophilic” adenoma)
Associated with
Primary amenorrhea
Turner syndrome (XO)
Associated with
Primary bone tumor (adults)
Multiple Myeloma
Associated with
Primary hyPERaldosteronism
Adenoma of adrenal cortex
Associated with
Primary hyPERparathyroidism
Adenomas, hyperplasia, carcinoma
Associated with
Primary liver cancer
Hepatocellular carcinoma from: Chronic hepatitis Cirrhosis Hemachromatosis a1 antitrypsin deficiency
Associated with
Pulmonary hypertension
COPD
Associated with
Recurrent inflammation/thrombosis of small or medium vessels in extremities
Buerger’s disease
Strongly associated w/ TOBACCO
Associated with
Renal tumor
Renal cell carcinoma:
Associated w/ von Hippel-Lindau
& with cigarette smoking
Paraneoplastic syndromes created by renal cell carcinoma:
Erythropoietin
PTH
ACTH
Associated with
R Heart failure due to a pulmonary cause
Cor pulmonale
Associated with
S3 (Protodiastolic gallop)
High ventricular filling
LV failure (CHF)
Mitral regurgitation
L–>R shunt
Associated with
S4 (Presystolic gallop)
Stiff/hypertrophic ventricle
Aortic stenosis
Restrictive cardiomyopathy
Associated with
Secondary HYPERparathyroidism
Caused by HyPOcalcemia of chronic kidney disease
Associated with
Sexually transmitted disease
Chlamydia (usually coinfected w/ gonorrhea)
Associated with
SIADH
Small cell carcinoma of the lung (causes SIADH)
Associated with
Site of diverticula
Sigmoid colon
Associated with
Sites of atherosclerosis
Abdominal aorta
> Coronary artery
> Popliteal artery
> Carotid artery
Associated with
Stomach cancer
Adenocarcinoma
Associated with
Stomach ulcerations & high gastrin levels
Zollinger-Ellison syndrome
Gastrinoma of DUODENUM or PANCREAS
Associated with
t(14;18)
Follicular lymphomas
bcl-2 activation
Associated with
t(8;14)
Burkitt’s lymphoma
c-myc activation
Associated with
t(9;22)
CML
Philadelphia chromosome
brc-able Tyrosine kinase
Associated with
Temporal arteritis
Polymyalgia rheumatica
Risk of IPSILATERAL blindness
due to thrombosis of OPTHALMIC ARTERY
Associated with
Testicular tumor
Seminoma
Associated with
Thyroid cancer
Papillary carcinoma
Associated with
Tumor in women
Leiomyoma
Estrogen-dependent; not precancerous
Associated with
Tumor of infancy
Hemangioma
usually regresses spontaneously by childhood
Associated with
Tumor of the adrenal medulla (Adults)
Pheochromocytoma (usually benign)
Associated with
Tumor of the adrenal medulla (Kids)
Neuroblastoma (malignant)
Associated with
Type of Hodgkin’s
Nodular sclerosis
vs. mixed cellularity, lymphocytic predominance, lymphocytic depletion
Associated with
Type of non-Hodgkins
Diffuse Large Cell
Associated with
UTI
E.coli Staph saprophyticus (young women)
Associated with
Viral encephalitis affecting TEMPORAL LOBE
HSV-1
Associated with
Vitamin deficiency (U.S.)
Folate
Pregnant women at high risk; body only stores 3-to-4-month supply; prevents NEURAL TUBE DEFECTS