Kety et al

Question 1

Aim

Answer 1

Does schiz have a genetic component through the comparison of adopted vs biological families?

Question 2

Participants

Answer 2

34 schiz patients from 503 adoptees in psychiatric hospitals and 33 healthy controls

Question 3

How were they matched?

Answer 3

Age, gender, social class and age of adoption

Question 4

How were the schizophrenics sorted?

Answer 4

B1 = chronic B2 = acute B3 = borderline

Question 5

How did they locate the adoptive and biological relatives? How many relatives did they get?

Answer 5

The Danish adoption register and 463 relatives

Question 6

Method of sorting relations?

Answer 6

4 Danish psychiatrists diagnosed relatives into D1 = chronic D2 = acute D3 = borderline C = inadequate personality

Question 7

Why was it a ‘blind test’?

Answer 7

Because they didn’t know if the relatives were A or B

Question 8

Results

Answer 8

Of 150 bio relatives of schiz pps, 13 (8.7%) had a schiz diagnosis vs 1.5% of bio relations in control group

Question 9

Conclusions

Answer 9

There is a genetic component to schiz as schiz adoptees are more likely to have schiz in bio families than adoptive families

Question 10

Generalizability

Answer 10

Large sample size, males and females, large age range

But ethnocentric as only one culture (Danish)

Question 11

Applicability

Answer 11

Applicable to diathesis stress model genetic predisposition yet triggered by traumatic event. Positive implications for society guiding children through stress and away from drugs, getting early diagnosis etc…

Question 12

Jay Joseph

Answer 12

Decreases reliability as he generalized milder mental illnesses with schiz ‘schizophrenic spectrum’
Only 1 family member with borderline schiz the rest were type c, very vague could just be eccentricity

Question 13

Validity

Answer 13

Increases validity as used Danish adoption register and the experiment was blind reducing experimenter bias