Keller Bugs and Drugs - Gram Negative Flashcards

1
Q

Neisseria gonorrhoeae - gonorrhea

A

Ceftriaxone

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2
Q

Neisseria gonorrhoeae - gonococcal pharyngitis

A

Ceftriaxone

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3
Q

Neisseria meningitidis - meningitis, bacteremia

A

Ceftriaxone

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4
Q

Moraxella cattharalis - Otitis media

A

Amoxicillin

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5
Q

Klebsiella pneumoniae - Pneumonia, bacteremia

A

Cephalosporin +/- aminoglycoside

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6
Q

Escherichia coli - ETEC

A

Ciprofloxacin (if warranted)

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7
Q

Escherichia coli - EHEC

A

Contraindicated

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8
Q

Escherichia coli - HUS from EHEC

A

Eculizumab

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9
Q

Escherichia coli - EIEC

A

Fluoroquinolone (if warranted)

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10
Q

Escherichia coli - Meningitis

A

3rd-gen cephalosporin (ceftriaxone)

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11
Q

Escherichia coli - Pneumonia

A

3rd-gen cephalosporin or fluoroquinolone

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12
Q

Escherichia coli - UTI (UPEC)

A

fluoroquinolone, TMP-SMX, or nitrofurantoin

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13
Q

Shigella - Bloody colitis

A

Fluoroquinolone (if warranted)

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14
Q

Salmonella - Nontyphoidal

A

Fluoroquinolone (if warranted)

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15
Q

Salmonella - Typhoidal

A

Fluoroquinolone (adult), ceftriaxone (children)

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16
Q

Pseudomonas - Endocarditis, bacteremia

A

Aminoglycoside + antipseudomonal b-lactam (piperacillin, ticarcillin, ceftazidime, cefepime, imipenem)

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17
Q

Pseudomonas - Meningitis

A

Ceftazidime

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18
Q

Pseudomonas - Osteomyelitis

A

beta-lactam, carbapenem or fluoroquinolone

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19
Q

Pseudomonas - UTI

A

Aminoglycoside or fluoroquinolone

20
Q

Vibrios - Cholera, parahaemolyticus

A

Fluids and electrolytes

21
Q

Yersinia pestis - Plague

A

Streptomycin (gentamicin)

22
Q

Francisella tularensis - tularemia

A

Streptomycin (gentamicin)

23
Q

Pseudomonas - Pneumonia

A
  1. Antipseudomonal beta-lactam + antipseudomonal quinolone (ciprofloxacin, levofloxacin)
  2. Antipseudomonal beta-lactam + aminoglycoside
  3. Antipseudomonal quinolone + aminoglycoside
24
Q

Neisseria gonorrhoeae - gonorrhea

A

Ceftriaxone

25
Q

Moraxella cattharalis - Otitis media

A

Amoxicillin

26
Q

Escherichia coli - ETEC

A

Ciprofloxacin (if warranted)

27
Q

Escherichia coli - EHEC

A

Contraindicated

28
Q

Escherichia coli - Meningitis

A

3rd-gen cephalosporin (ceftriaxone)

29
Q

Escherichia coli - Pneumonia

A

3rd-gen cephalosporin or fluoroquinolone

30
Q

Shigella - Bloody colitis

A

Fluoroquinolone (if warranted)

31
Q

Salmonella - Nontyphoidal

A

Fluoroquinolone (if warranted)

32
Q

Pseudomonas - Endocarditis, bacteremia

A

Aminoglycoside + antipseudomonal b-lactam (piperacillin, ticarcillin, ceftazidime, cefepime, imipenem)

33
Q

Pseudomonas - Osteomyelitis

A

beta-lactam, carbapenem or fluoroquinolone

34
Q

Vibrios - Cholera, parahaemolyticus

A

Fluids and electrolytes

35
Q

Campylobacter - Bloody diarrhea

A

Fluoroquinolone or azithromycin

36
Q

Helicobacter pylori - Gastric ulcer

A

PPI + amoxicillin + clarithromycin

37
Q

Haemophilus influenzae - Otitis media

A

Amoxicillin

38
Q

Haemophilus influenzae - Meningitis

A

Ceftriaxone

39
Q

Yersinia pestis - Plague

A

Streptomycin (gentamicin)

40
Q

Bordetella pertussis - pertussis

A

Macrolide (historically erythromycin)

41
Q

Pasteurella multocida - cellulitis

A

amoxicillin-clavulanate

42
Q

Francisella tularensis - tularemia

A

Streptomycin (gentamicin)

43
Q

Legionella pneumophila - Legionnaires disease

A

Levofloxacin or azithromycin

44
Q

Legionella pneumophila - transplant pts

A

Levofloxacin

45
Q

Brucella spp. - brucellosis

A

Doxy + streptomycin

46
Q

Bacteroides - intraabdominal abscess

A

metronidazole

47
Q

HACEK - Endocarditis

A

Ceftriaxone