KA6- Specific Cellular Defences Against Pathogens

Question 1

Lymphocytes are

Answer 1

the white blood cells involved in the specific immune response

Question 2

Lymphocytes respond

Answer 2

to specific antigens on invading pathogens

Question 3

Antigen binding

Answer 3

Leads to repeated lymphocyte division resulting in the formation of clonal population of identical lymphocytes

Question 4

Type of lymphocyte

Answer 4

Move to and mature in the thymus gland develop into T
Remain and mature in the bone marrow develop into B

Question 5

B lymphocytes produce

Answer 5

Antibodies against antigens and this leads to the destruction of the pathogen

Question 6

B lymphocytes can respond

Answer 6

To antigens on substances that are harmless to the body, eg pollen.
This hypersensitive response is called an allergic reaction

Question 7

Failure of regulation of immune system leads

Answer 7

To T lymphocytes responding to self-antigens which causes autoimmune diseases

Question 8

In autoimmunity

Answer 8

The T lymphocytes attack the body’s own cells. This causes autoimmune diseases such as type 1 diabetes and rheumatoid arthritis

Question 9

HIV

Answer 9

Human immunodeficiency virus attacks and destroys T lymphocytes

Question 10

HIV causes

Answer 10

Depletion of T lymphocytes which leads to the development of AIDS

Question 11

AIDS

Answer 11

Acquired immune deficiency syndrome.

Question 12

Individuals with AIDS have

Answer 12

A weakened immune system and so are more vulnerable to opportunistic infections