KA5: protein control of cell division: the cell cycle Flashcards
what does the cell cycle consist of?
interphase and mitotic (M) phase
name the three stages of interphase
G1, S, G2
describe each phase of interphase
Involves growth and DNA synthesis including
G1, a growth phase
S phase, during which the DNA is replicated
G2, a further growth phase.
What does the mitotic phase consist of?
mitosis and cytokinesis
briefly describe each part of the mitotic phase
mitosis=> the chromosomal material is separated by the spindle microtubules.
cytokinesis => the cytoplasm is separated into two daughter cells.
list the 4 stages of mitosis
-prophase
-metaphase
-anaphase
-telophase
Describe Prophase of Mitosis
DNA condenses into chromosomes each consisting of two sister chromatids.
Nuclear membrane breaks down
spindle microtubules extend from the MTOC by polymerisation and attach to chromosomes via their kinetochores in the centromere region
describe the metaphase of mitosis
chromosomes are aligned at the metaphase plate (equator of the spindle)
describe the anaphase of mitosis
-spindle microtubules shorten by depolymerisation
-sister chromatids are separated
-the chromosomes are pulled to opposite poles
describe the telophase of mitosis
-chromosomes decondense
-nuclear membranes are formed around them
draw the cell cycle diagram
answers in textbook3