KA5- Human Genomics Flashcards
The genome of an organism
is it’s entire hereditary information encoded in DNA
A genome
is made up of genes and other DNA sequences that do not code for proteins
An individual’s genome
can be analysed to predict the likelihood of developing certain diseases
Pharmacogenetics
is the use of genome information in the choice of drugs
Personalised medicine
An individual’s personal genome sequence can be used to select the most effective drugs and dosage to treat their disease (personal medicine).
DNA sequences
that code for protein are defined as genes. Other sequences regulate transcription and others are transcribed but never translated.
Genomic sequencing
the sequence of nucleotides bases can be determined for individual genes and entire genomes
Computer programs (genomic sequencing)
Identify base sequences by looking for sequences similar to known genes
To compare sequence data
Computer
Statistical analyses
Genetic data
(Bioinformatics)