KA3- Gene Expression Flashcards
Gene expression
Involves the transcription and translation of DNA sequences
Only a fraction of the genes in a cell are expressed
mRNA
Carries a copy of the DNA code from the nucleus to the ribosome
Is transcribed from DNA in the nucleus and translated into proteins by ribosomes in the cytoplasm
tRNA
Folds due to complementary base pairing. Each tRNA molecule carries its specific amino acid to the ribosome
A tRNA a molecule has an anticodon (an exposed triplet of bases) at one end and an attachment site for a specific amino acid at the other end
rRNA
Ribosomal RNA
And proteins form the ribosome
Result of alternative RNA splicing
Different proteins can be expressed from one gene, as a result of alternative RNA splicing
Different mature mRNA transcripts are produced from the same primary transcript depending on which exons are retained
Protein structure
Amino acids are linked by peptide bonds to form polypeptides
Polypeptide chains fold to form the three-dimensional shape of a protein, held together by hydrogen bonds and other interactions between individual amino acids
Proteins have a large variety of shapes which determines their functions
Phenotype
Is determined by proteins produced as a result of gene expression
Environmental factors also influence phenotype