Juvenile Dermatomyositis Flashcards
MC inflammatory myositis in children
JDM
Rheuma: Proximal muscle weakness and a characteristic rash
JDM
JDM, T/F: History of infection is commonly reported
T, in the past 3 months
JDM: First symptom in 50% of cases
Rash
JDM, T/F: Rash appears concomitant with weakness in a vast majority
F, 25% of the time
Rheuma: Shawl sign
JDM, erythema over chest and neck from extreme photosensitivity to UV light
Rheuma: Heliotrope rash
JDM, Blue-violet discoloration of eyelids
Rheuma: Gottron papules
JDM
Bright pink or pale shiny thickened ATROPHIC plaques over the PIP and DIP and occasionally on other areas seen in JDM
Gottron papules
Rheuma: Mechanic’s hand
JDM
Thickened erythema and scaly rash in children over the palms and soles along the flexor tendons
Mechanic’s hand
Mechanic’s hand is associated with what antibodies
Anti-Jo-1 antibodies
Rheuma: Gower sign
JDM
JDM, T/F: Muscle weakness is symmetric
T
JDM, T/F: Characterized by head lag in a child after infancy
T
Use of hands on thighs to stand from a sitting position
Gower’s sign
Associated with long-standing JDM
1) Lipodystrophy 2) Calcinosis
JDM: Criteria for diagnosis
Characteristic rash (Heliotrope or Gottron) + at least 3 of the ff: 1) Muscle weakness (symmetric, proximal) 2) Muscle enzyme elevation (CK, AST, LDH, aldolase) 3) EMG changes (myopathy, denervation) 4) Muscle biopsy (necrosis, inflammation)
JDM that presents with classic rash but no apparent muscle weakness or inflammation
Amyopathic JDM
Mainstay of therapy in JDM
Corticosteroids