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52 > just things to take note > Flashcards

just things to take note Flashcards

1
Q

what is the component of phospholipid with the highest percentage in plasma membranes

A

phosphatidycholine

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2
Q

what is the importance of linolenic acid

A

reduce inflammation

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3
Q

what is the importance of linoleic acid`

A

precursoe for arachidonic acid

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4
Q

what are the fat soluble vitamins

A

A, D,E,K

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5
Q

example of lipid soluble anti oxidants which are not vitamins

A

alpha-tocopherol
beta-carotene

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6
Q

what is COX full name

A

cyclooxygenase

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7
Q

what are some cox inhibitors

A

aspirin

naproxen –> structurally similar so it is a competitive inhibitor which mimics critical fatty acid-dependent interactions at active site

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8
Q

what are the inhibitors for cholesterol synthesis

A

statin

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9
Q

what are the inhibitors for choesterol uptake

A

ezetimibe - blocks the sterol transporter preventing dietary cholesterol uptake

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10
Q

what are some hormone receptor inhibitors

A

tamoxifen ( estrogen)
flutamide (androgen)

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11
Q

why are carbohydrates not reliable as permananent storage sources

A

they are more soluble in water

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12
Q

what is heparin and its mechanism

A

heparin is an anti-coagulant
heparin binds to anti-thrombin 3–> activates it–> inhibits thrombin –> inhibit formation of clots

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13
Q

what is the formula for V0

A

v0 = vmax (concentration of substrate) / kmax + concentration of substrate

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14
Q

what is omeprazole

A

proton pump inhibitor

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15
Q

what is the action of omeprazole

A

blocks the K+ and hydrigen anti porter –> no secretion –> gastric acid is reduced

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16
Q

what is an anti-histimine receptor example and its action

A

chlorpheniramine

binds to the receptor binding site of histimine receptors reducing cell signalling

17
Q

what is an example of antibodies as therapuetic blockage

A

dupilumab il4a monoclonal antibodies

18
Q

what is the action of dupilumab il4a

A

block the convergent point for inflammatory responses –> no inflammatory response

19
Q

what are some examples of peptidomimetics

A

sulfonamide
thioester
retroinverso
peptoid

20
Q

the deal with tropocollagen and collagen

A
21
Q

what happens to collagen if no vit c

A

collagen fibres are weakened as vit c is a cofactor

22
Q

what is the intracellular ph range

A

6.8-7.4

23
Q
A

52 (3 decks)

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