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Pharmaceutics IV Test 2 > Just Ointment Bases > Flashcards

Just Ointment Bases Flashcards

1
Q

Oleaginous Ointment Base Composition

A

Hydrocarbon, oleaginous compounds

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2
Q

Absorption Ointment Base Type 1 Composition

A

Oleaginous base + w/o surfactant

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3
Q

Absorption Ointment Base Type 2 Composition

A

Oleaginous base + water (less than 45% w/w) + w/o surfactant HLB less than 8

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4
Q

Water-Removable Ointment Base Composition

A

oleaginous base + water (greater than 45% w/w) + o/w surfactant HLB greater than 8

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5
Q

Water-Soluble Ointment Base Composition

A

Polyethylene Glycols (PEGS)

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6
Q

Oleaginous Ointment Base water content

A

anhydrous

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7
Q

Absorption Ointment Base Type 1 water content

A

anhydrous

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8
Q

Absorption Ointment Base Type 2 water content

A

hydrous

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9
Q

Water-Removable Ointment Base water content

A

hydrous

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10
Q

Water-Soluble Ointment Base water content

A

anhydrous, hydrous

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11
Q

Oleaginous Ointment Base affinity for water

A

Hydrophobic

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12
Q

Absorption Ointment Base Type 1 affinity for water

A

Hydrophilic

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13
Q

Absorption Ointment Base Type 2 affinity for water

A

Hydrophilic

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14
Q

Water-Removable Ointment Base affinity for water

A

Hydrophilic

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15
Q

Water-Soluble Ointment Base affinity for water

A

Hydrophilic

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16
Q

Oleaginous Ointment Base spreadability

A

difficult

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17
Q

Absorption Ointment Base Type 1 spreadability

A

difficult

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18
Q

Absorption Ointment Base Type 2 spreadability

A

moderate to easy

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19
Q

Water-Removable Ointment Base spreadability

A

easy

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20
Q

Water-Soluble Ointment Base spreadability

A

moderate to easy

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21
Q

Oleaginous Ointment Base washability

A

nonwashable

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22
Q

Absorption Ointment Base Type 1 washability

A

nonwashable

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23
Q

Absorption Ointment Base Type 2 washability

A

non- or poorly washable

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24
Q

Water-Removable Ointment Base washability

A

washable

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25
Q

Water-Soluble Ointment Base washability

A

washable

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26
Q

Oleaginous Ointment Base stability

A

oils poor; hydrocarbons better

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27
Q

Absorption Ointment Base Type 1 stability

A

oils poor; hydrocarbons better

28
Q

Absorption Ointment Base Type 2 stability

A

unstable, especially alkali soaps and natural colloids

29
Q

Water-Removable Ointment Base stability

A

unstable, especially alkali soaps and natural colloids, nonionic better

30
Q

Water-Soluble Ointment Base stability

A

stable

31
Q

Oleaginous Ointment Base drug incorporation potential

A

solids or oils (oil solubles only)

32
Q

Absorption Ointment Base Type 1 drug incorporation potential

A

solids, oils, and aqueous solutions (small amounts)

33
Q

Absorption Ointment Base Type 2 drug incorporation potential

A

solids, oils, and aqueous solutions (small amounts)

34
Q

Water-Removable Ointment Base drug incorporation potential

A

solid and aqueous solutions (small amounts)

35
Q

Water-Soluble Ointment Base drug incorporation potential

A

solid and aqueous solutions

36
Q

Oleaginous Ointment Base drug release potential

A

poor

37
Q

Absorption Ointment Base Type 1 drug release potential

A

poor, but better than oleaginous

38
Q

Absorption Ointment Base Type 2 drug release potential

A

fair to good

39
Q

Water-Removable Ointment Base drug release potential

A

fair to good

40
Q

Water-Soluble Ointment Base drug release potential

A

good

41
Q

Oleaginous Ointment Base occlusiveness

A

yes

42
Q

Absorption Ointment Base Type 1 occlusiveness

A

yes

43
Q

Absorption Ointment Base Type 2 occlusiveness

A

sometimes

44
Q

Water-Removable Ointment Base occlusiveness

A

no

45
Q

Water-Soluble Ointment Base occlusiveness

A

no

46
Q

Oleaginous Ointment Base uses

A

protectants, emollients (+/-), vehicles for hydrolyzable drugs

47
Q

Absorption Ointment Base Type 1 uses

A

protectants, emollients (+/-), vehicles for aqueous solutions, solids, and non-hydrolyzable drugs

48
Q

Absorption Ointment Base Type 2 uses

A

emollients, cleansing creams, vehicles for solid, liquid, or non-hydrolyzable drugs

49
Q

Water-Removable Ointment Base uses

A

emollients, vehicles for solid, liquid, or non-hdyrolyzable drugs

50
Q

Water-Soluble Ointment Base uses

A

drug vehicles

51
Q

Oleaginous Ointment Base examples

A

White Petrolatum, White Ointment

52
Q

Absorption Ointment Base Type 1 examples

A

hydrophilic Petrolatum, Anhydrous Lanolin, Aquabase, Aquaphor, Polysorb

53
Q

Absorption Ointment Base Type 2 examples

A

Cold Cream type, Hydrous Lanolin, Rose Water Ointment, Hydrocream, Eucerin, Nivea

54
Q

Water-Removable Ointment Base examples

A

Hydrophilic Ointment, Vanishing cream, Parabenes, Dermabase, Velvachol, Unibase

55
Q

Water-Soluble Ointment Base examples

A

PEG Ointment, Polybase

56
Q

Oleaginous Ointment Base advantages

A

Inexpensive, non-irritating stays on skin, best emollient, protective, no microbial growth

57
Q

Absorption Ointment Base Type 1 advantages

A

Moderate emollient and protective, stays on skin, can absorb some liquids

58
Q

Absorption Ointment Base Type 2 advantages

A

Moderate emollient and protective, stays on skin, can absorb some liquids

59
Q

Water-Removable Ointment Base advantages

A

Non-greasy, washable, can absorb some water/alcohol, will allow dissipation of fluid from skin (absorb serous discharge)

60
Q

Water-Soluble Ointment Base advantages

A

Soluble in water so washable, no oil residue, can absorb some water/alcohol

61
Q

Oleaginous Ointment Base disadvantages

A

Very greasy, not easily washable, can’t absorb water

62
Q

Absorption Ointment Base Type 1 disadvantages

A

Not easily washable, may be sensitizing, compatibility/stability issues because hydrolysis, can have microbial growth

63
Q

Absorption Ointment Base Type 2 disadvantages

A

Not easily washable, may be sensitizing, compatibility/stability issues because hydrolysis, can have microbial growth

64
Q

Water-Removable Ointment Base disadvantages

A

Less protective, less emollient effect, compatibility/stability issues because hydrolysis, microbial growth, may dry out

65
Q

Water-Soluble Ointment Base disadvantages

A

Irritating, no emollient effect, compatibility/stability issues with PEG because oxidation, microbial growth

Pharmaceutics IV Test 2 (7 decks)

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