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Pharmaceutics IV Test 2 > Just Ointment Bases > Flashcards

Just Ointment Bases Flashcards

1
Q

Oleaginous Ointment Base Composition

A

Hydrocarbon, oleaginous compounds

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2
Q

Absorption Ointment Base Type 1 Composition

A

Oleaginous base + w/o surfactant

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3
Q

Absorption Ointment Base Type 2 Composition

A

Oleaginous base + water (less than 45% w/w) + w/o surfactant HLB less than 8

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4
Q

Water-Removable Ointment Base Composition

A

oleaginous base + water (greater than 45% w/w) + o/w surfactant HLB greater than 8

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5
Q

Water-Soluble Ointment Base Composition

A

Polyethylene Glycols (PEGS)

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6
Q

Oleaginous Ointment Base water content

A

anhydrous

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7
Q

Absorption Ointment Base Type 1 water content

A

anhydrous

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8
Q

Absorption Ointment Base Type 2 water content

A

hydrous

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9
Q

Water-Removable Ointment Base water content

A

hydrous

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10
Q

Water-Soluble Ointment Base water content

A

anhydrous, hydrous

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11
Q

Oleaginous Ointment Base affinity for water

A

Hydrophobic

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12
Q

Absorption Ointment Base Type 1 affinity for water

A

Hydrophilic

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13
Q

Absorption Ointment Base Type 2 affinity for water

A

Hydrophilic

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14
Q

Water-Removable Ointment Base affinity for water

A

Hydrophilic

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15
Q

Water-Soluble Ointment Base affinity for water

A

Hydrophilic

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16
Q

Oleaginous Ointment Base spreadability

A

difficult

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17
Q

Absorption Ointment Base Type 1 spreadability

A

difficult

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18
Q

Absorption Ointment Base Type 2 spreadability

A

moderate to easy

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19
Q

Water-Removable Ointment Base spreadability

A

easy

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20
Q

Water-Soluble Ointment Base spreadability

A

moderate to easy

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21
Q

Oleaginous Ointment Base washability

A

nonwashable

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22
Q

Absorption Ointment Base Type 1 washability

A

nonwashable

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23
Q

Absorption Ointment Base Type 2 washability

A

non- or poorly washable

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24
Q

Water-Removable Ointment Base washability

A

washable

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25
Water-Soluble Ointment Base washability
washable
26
Oleaginous Ointment Base stability
oils poor; hydrocarbons better
27
Absorption Ointment Base Type 1 stability
oils poor; hydrocarbons better
28
Absorption Ointment Base Type 2 stability
unstable, especially alkali soaps and natural colloids
29
Water-Removable Ointment Base stability
unstable, especially alkali soaps and natural colloids, nonionic better
30
Water-Soluble Ointment Base stability
stable
31
Oleaginous Ointment Base drug incorporation potential
solids or oils (oil solubles only)
32
Absorption Ointment Base Type 1 drug incorporation potential
solids, oils, and aqueous solutions (small amounts)
33
Absorption Ointment Base Type 2 drug incorporation potential
solids, oils, and aqueous solutions (small amounts)
34
Water-Removable Ointment Base drug incorporation potential
solid and aqueous solutions (small amounts)
35
Water-Soluble Ointment Base drug incorporation potential
solid and aqueous solutions
36
Oleaginous Ointment Base drug release potential
poor
37
Absorption Ointment Base Type 1 drug release potential
poor, but better than oleaginous
38
Absorption Ointment Base Type 2 drug release potential
fair to good
39
Water-Removable Ointment Base drug release potential
fair to good
40
Water-Soluble Ointment Base drug release potential
good
41
Oleaginous Ointment Base occlusiveness
yes
42
Absorption Ointment Base Type 1 occlusiveness
yes
43
Absorption Ointment Base Type 2 occlusiveness
sometimes
44
Water-Removable Ointment Base occlusiveness
no
45
Water-Soluble Ointment Base occlusiveness
no
46
Oleaginous Ointment Base uses
protectants, emollients (+/-), vehicles for hydrolyzable drugs
47
Absorption Ointment Base Type 1 uses
protectants, emollients (+/-), vehicles for aqueous solutions, solids, and non-hydrolyzable drugs
48
Absorption Ointment Base Type 2 uses
emollients, cleansing creams, vehicles for solid, liquid, or non-hydrolyzable drugs
49
Water-Removable Ointment Base uses
emollients, vehicles for solid, liquid, or non-hdyrolyzable drugs
50
Water-Soluble Ointment Base uses
drug vehicles
51
Oleaginous Ointment Base examples
White Petrolatum, White Ointment
52
Absorption Ointment Base Type 1 examples
hydrophilic Petrolatum, Anhydrous Lanolin, Aquabase, Aquaphor, Polysorb
53
Absorption Ointment Base Type 2 examples
Cold Cream type, Hydrous Lanolin, Rose Water Ointment, Hydrocream, Eucerin, Nivea
54
Water-Removable Ointment Base examples
Hydrophilic Ointment, Vanishing cream, Parabenes, Dermabase, Velvachol, Unibase
55
Water-Soluble Ointment Base examples
PEG Ointment, Polybase
56
Oleaginous Ointment Base advantages
Inexpensive, non-irritating stays on skin, best emollient, protective, no microbial growth
57
Absorption Ointment Base Type 1 advantages
Moderate emollient and protective, stays on skin, can absorb some liquids
58
Absorption Ointment Base Type 2 advantages
Moderate emollient and protective, stays on skin, can absorb some liquids
59
Water-Removable Ointment Base advantages
Non-greasy, washable, can absorb some water/alcohol, will allow dissipation of fluid from skin (absorb serous discharge)
60
Water-Soluble Ointment Base advantages
Soluble in water so washable, no oil residue, can absorb some water/alcohol
61
Oleaginous Ointment Base disadvantages
Very greasy, not easily washable, can't absorb water
62
Absorption Ointment Base Type 1 disadvantages
Not easily washable, may be sensitizing, compatibility/stability issues because hydrolysis, can have microbial growth
63
Absorption Ointment Base Type 2 disadvantages
Not easily washable, may be sensitizing, compatibility/stability issues because hydrolysis, can have microbial growth
64
Water-Removable Ointment Base disadvantages
Less protective, less emollient effect, compatibility/stability issues because hydrolysis, microbial growth, may dry out
65
Water-Soluble Ointment Base disadvantages
Irritating, no emollient effect, compatibility/stability issues with PEG because oxidation, microbial growth

Pharmaceutics IV Test 2 (7 decks)

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