Joints, Synovial Fluids and Cartilage Flashcards

1
Q

Which joints are fibrous joints

A

Peridontal Ligament, the cranial sutures and the interosseous membranes

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2
Q

Describe a fibrous joint

A

At a fibrous joint, the adjacent bones are directly connected to each other by fibrous connective tissue, and thus the bones do not have a joint cavity between them

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3
Q

State the three types of fibrous joints

A

Sutures, Gomphoses and Syndesmoses

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4
Q

Sutures

A

Immovable joints only found between, the flat plate like bones of the skull

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5
Q

When are suture joints important

A

At birth

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6
Q

Gomphoses

A

Immovable joint where the teeth articulate with their sockets in the maxillae or the mandible

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7
Q

Syndesmosis

A

Movable joints in which bones are held together by an interosseus membrane

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8
Q

What are the function of syndesmosis joints

A

Provide strength along the length of long bones

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9
Q

Give examples of syndesmosis joints

A

Middle radio-ulnar and the middle tibiofibular joints

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10
Q

In cartilaginous joints, what are the bones attached by

A

Fibro or hyaline cartilage

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11
Q

What type of cartilage do synchondroses or primary cartilaginous joints contain

A

Hyaline

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12
Q

Give an example of a primary cartilaginous joint

A

Between the diaphysis and epiphysis

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13
Q

symphyses

A

Involve either hyaline or fibrocartilage and are slightly movable. An example is the pubic symphysis

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14
Q

Hinge synovial joint

A

Permits flexion and extension. Elbow joint is an example

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15
Q

Saddle synovial joint

A

Concave and convex joint surfaces unite at saddle joints. An example is the metatarsophalangeal joint

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16
Q

Plane synovial joint

A

Permits gliding or sliding movements. Example is the acromioclavicular joint

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17
Q

Pivot synovial joint

A

Allows rotation; a round bony process fits into a bony ligamentous socket. Examples are the atlantoaxial joint and the proximal radio-ulnar joint

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18
Q

Condyloid synovial joint

A

Permits flexion, extension, adduction, abduction and circumduction. Metacarpophalangeal joint (middle of the hand)

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19
Q

Ball and socket synovial joint

A

Permits movement in several axis, an example is the glenohumeral joint

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20
Q

The articular cartilage of synovial joints is made up of

A

Hyaline cartilage

21
Q

Describe the superficial/tangential layer of cartilage

A

Made up of flattened chondrocytes that produce collagen and glycoproteins (lubricin)

22
Q

Describe the transitional layer of cartilage

A

Round chondrocytes that produce proteoglycans from superifical to deep levels

23
Q

State the main functions of cartilage

A

Supporting the framework of organs, form the articulating surfaces of bones and growth and development of long bones

24
Q

Which cartilage is the weakest

A

Hyaline cartilage

25
Q

Describe the collagen fibres in hyaline cartilage

A

Widely dispersed thin type 2

26
Q

Strongest type of cartilage

A

Fibrocartilage

27
Q

Describe the structure of fibrocartilage

A

alternating layers of hyaline cartilage matrix and thick layers of dense collagen fibres orientated in the direction of functional stresses

28
Q

Describe the structure of elastic cartilage

A

The chondrocytes are found in a threadlike network of elastic fibres in the matrix

29
Q

What are the constituents of cartilage

A

Chondroblasts, chondrocytes and extracellular matrix (10% aggrecan, 75% water and a mix of collagen fibres)

30
Q

State the function of chondroblasts

A

Secrete matrix and fibres into the ECM of cartilage

31
Q

What are chondrocytes

A

Trapped chondroblasts which have matured into chondrocytes

32
Q

What are lacunae

A

Matrix encolsed comparments that chondrocytes sit in

33
Q

The surface of most cartilage is covered by

A

A layer of dense irregular connective tissue called the perichondrium

34
Q

What does the outer layer of the periochondrium contain

A

Collagen producing fibroblasts

35
Q

What does the inner layer of the perichondrium contain

A

Chondroblasts

36
Q

What is the vascularity of cartilage

A

Avascular

37
Q

How does cartilage get nourished

A

Long range diffusion from nearby capillaries in the perichondrium

38
Q

Interstitial growth of cartilage

A

Chondrocytes grow and divide and lay down more matrix inside existing cartilage

39
Q

Appositional growth of cartilage

A

New surface layers of matrix are added to the pre-existing matrix by new chondroblasts from the perichondrium

40
Q

How is articular cartilage nourished

A

From the synovial fluid produced by the synovial membrane

41
Q

What cells produce synovial fluid

A

Synoviocytes

42
Q

Type A synoviocytes

A

Look like macrophages. These remove debris and contribute to fluid production.

43
Q

Type B synoviocytes

A

Fibroblast-like and main producer of synovial fluid

44
Q

What is synovial fluid made up of

A
  • Viscous fluid
  • Hyaluronic acid and lubricin, collagenases and proteinases
  • Fluid component
45
Q

State the functions of synovial fluid

A

Nutrition of articular cartilage, removal of waste products and lubrication

46
Q

Describe the process of lubrication

A

boundary including glycoproteins such as lubricin bind to receptors on articular surfaces to form a thin film. It is hydrodynamic – surfaces kept apart by liquid pressure and viscosity changes with load and velocity of movements

47
Q

What happens to the viscosity of synovial fluid as age increases

A

Increases, slower joint movements and reduced lubrication

48
Q

What happens to the water content of cartilage as age increases

A

Decreases - therefore reduced shock absorption