Joints, synovial fluid and cartilage Flashcards

1
Q

What are the three types of joints

A

Fibrous
Cartilagenous
Synovial

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2
Q

Describe fibrous joints

A

Not much movement
Strong
Collagen fibres inbetween bones

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3
Q

Where are fibrous joints found

A

Found in skull (periodontal ligament and cranial sutures

Also interosseous membrane

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4
Q

Describe cartilaginous joints

A

Cartilage between

Primary or secondary

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5
Q

Describe a primary cartilaginous joint

A

Only hyaline cartilage – SYNCHONDROSIS

Found on growth plate

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6
Q

Describe a secondary cartilaginous joint

A

hyaline & fibrocartilage – SYMPHYSIS

Found in intervertebral disc

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7
Q

What are the types of synovial joint

A
  • Hinge, Pivot, Saddle, Plane, Condylar, Ball and socket
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8
Q

What determines joint stability

A

Shape of articulating surfaces
Fibrous capsule and ligaments
Muscles
Cartilage (in synovial joints)

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9
Q

What is the type of cartilage found in synovial joints

A

Fibrocartilage

Hyaline cartilage

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10
Q

What does fibrocartilage look like and what is its function in synovial joints

A

Half moon shaped menisci which make the articulating surfaces fit better (increases movement and stability). They also play a role in shock absorption (because they are made up on fibrocartilage (v strong).

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11
Q

What does hyaline cartilage look like and what is its function in synovial joints

A

Hyaline cartilage : found In articular surfaces of joints. Also contains collagen but not as densely bound and so it weaker.

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12
Q

What kind of proteins are found in joints

A

Glycoprotein
Proteoglycans
Glycosaminoglycans

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13
Q

What is a glycoprotein

A

Glycoproteins (e.g. lubricin): proteins to which oligosaccharide chains are attached, i.e. more a protein than a carbohydrate!

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14
Q

What is a proteoglycan

A
  • Proteoglycans (e.g. aggrecan): proteins that are heavily glycosylated (= a protein core to which one or more GAGs attach), i.e. tend to be more carb than protein!-
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15
Q

What is a Glycosaminoglycans

A

Glycosaminoglycans or GAGs (e.g. hyaluronic acid): long unbranched polysaccharides, which are highly polar and thus attract water (helps maintain high water content)

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16
Q

What is a chondrocyte

A

A cartilage cell

17
Q

What do the chondrocytes look like and what to do they do at the superficial layer of hyaline cartilage

A

They are flattened and produce collagen and glycoproteins (lubricin)

18
Q

What do the chondrocytes look like and what to do they do at the transitional/deep layer of hyaline cartilage

A

They are round and produce proteoglycans (aggrecan)

19
Q

What % of hyaline cartilage is water and why is this important

A

> 75% water

Water is incompressible

20
Q

What 3 A words are used to describe cartilage

A

Avascular
Aneural
Alymphatic

21
Q

How does cartilage get its nutrients

A

The synovial fluids help provide nutrients to the cartilage. . It also helps with lubrication (less friction)

22
Q

Where is synovial fluid made

A

It is produced by synoviocytes in the synovial membrane (the synovium)

23
Q

Describe the synovium

A

Synoviocytes producing the fluid
Rich capillary network
No epithelial lining

24
Q

What exchanges at the synovium

A

Direct exchange of oxygen, carbon dioxide & metabolites between blood & synovial fluid

25
Q

What are the categories of synoviocyte

A

Type A

Type B

26
Q

Describe type A synoviocytes

A

Look like macrophages

Remove debris from tissue

Contribute to synovial fluid production

27
Q

Describe type B synoviocytes

A

Fibroblast like

Main producer of synovial fluid

28
Q

What does synovial fluid contain

A

Contains Hyaluronic acid & lubricin

29
Q

How long does it take to turnover synovial fluid

A

2 hours (rapid)

30
Q

What are the types of lubrication at a joint

A

Boundary
Hydrodynamic
Weeping

31
Q

What is boundary lubrication

A

Glycoproteins such as lubricin bind to receptors on articular surfaces to form a thin film
Hydrodynamic (like aquaplaning)

32
Q

What is Hydrodynamic lubrication

A

Surfaces kept apart by liquid pressure

Viscosity changes with load and velocity of movement

33
Q

What is weeping lubrication

A

Fluid that is present in the cartilage is squeezed out into the synovial cavity to increase fluid volume

34
Q

What happens to joints in the normal aging process

A

Viscosity of synovial fluid increases

   Slower joint movements

   Reduced lubrication

Water content of cartilage decreases

    Reduced shock 
   absorption