Joint conditions Flashcards
Is osteoarthritis an example of inflammatory or non-inflammatory arthritis? Is primary or secondary Osteoarthritis more common in dogs?
Non Inflammatory.
Secondary OSA is most common in dogs- also referred to as DJD- degenerative joint disease
Is septic arthritis an example of inflammatory or non-inflammatory arthritis? How do you treat it?
Inflammatory.
Treat by arthrotomy and joint lavage
What is the single most important element in the prevention or management of Osteoarthritis?
Weight management
NSAIDs are commonly used to treat Osteoarthritis. How do NSAIDs work?
Reduce pro-inflammatory mediators by inhibiting cyclooxygenase. (COX-2 is what you want to selectively inhibit). All NSAIDS have GI, renal and hepatic side effects and all are potentially toxic. Cats metabolize NSAIDS by glucuronidation, so NSAIDs are normally not indicated for cats.
What is the MOA of Omega-3 Fatty Acids for joint health?
Omega-3s compete with aracadonic acid as a substrate for COX-> produce less pro-inflammatory mediators. May decrease need for NSAIDs.
Osteochondrosis is a defect in _______ ossification.
What is the pathophysiology?
Osteochondrosis is a defect in endochondral ossification.
Path: Disruptions in anastamosis of vessels between the epiphyseal cartilage and bone create cartilage necrosis. This necrotic cartilage blocks the ossification wave, ad the necrotic cartilage cannot ossify.
Failure to ossify-> thickened cartilage.
Thickened cartilage acts as a stress riser-> fractures in cartilage.
T/F: For Osteochondritis Dessicans to manifest as a disease, you must have a combination of heritable and environmental factors.
True. Genetics, nutrition and trauma will influence OCD. Male dogs and large breed are predisposed. Do not breed dogs that exhibit disease.
If it is a developmental orthopedic disease it probably exhibits three characteristics. Describe them.
- Is heritable
- Is bilateral
- Has a biphasic age distribution
Can you diagnose biceps tendinopathy on radiograph?
Not really… maybe can see signs if you are experienced, but MRI and Arthroscopy is more diagnostic
In respect to shoulder instability in dogs, is medial or lateral instability more common?
Medial.
T/F: For shoulder instability, most cases will respond well to cage rest and NSAIDs.
FALSE. Cage rest and NSAIDs will often not improve the condition much.
How do you diagnose an abnormal abduction angle in a dog with medial shoulder instability?
Compare abduction angle to that of the contralateral limb. Abnormal is ~50 degrees
For shoulder instability, if you do not opt for surgery, what would the therapy include?
Velpeau sling followed by hobbles. LONG RECOVERY, 4-6 months.
T/F: Infraspinatus Contracture is a condition that can be diagnosed from “across the room.”
True. It is characterized by a specific posture of the forelimb. It is a non-painful, non-weightbearing lameness in which the elbow is adducted (drawn into the body) and the antebrachium is abducted (the forelimb is helf out away from the body)
What condition exhibits a “toed-out” posture?
Medial compartment dz/ elbow dysplasia
When I say UAP, you think ________.
Short Ulna!!!! Think U for Ulna.
When you hear FCP, you think ________.
Short Radius!!!
T/F: FCP is easily identified on radiographs?
False. Very difficult to id on rads bc the coronoid process is overlapped on every view you could take.
Gold standard for diagnosing is arthroscopy.
A bacterial arthritis as a result of surgery is an example or an inflammatory or non-inflammatory arthritis?
Inflammatory.
T/F: OCD and FCP are treated by arthroscopy surgery to remove fragments in the joint.
True. arthroscopy is the gold standard for visualizing the fractures and treating OCD and FCP. 90% of cases of FCP have concurrent OCD.
T/F: A medial meniscal release does not increase the risk of arthritis developing in a joint.
False. It does indeed increase the risk of arthritis developing.
T/F: Omega- 3 fatty acids act by increasing the amount of cartilage in a joint.
False! Omega 3s just act by converting cyclooxygenase