Jepordy Flashcards
This major adrenal glucocorticoid raises blood glucose and also anti-inflammatory effects
cortisol
It is a life threatening condition (freq autoimmune) characterized by abnormal skin pigmentation and can cause death by circulatory collapse secondary to Na+ depletion?
Addison’s disease
Its the most common second messenger system for protein or peptide hormones
adenyl cyclase-cyclic AMP 2nd messenger signaling
It’s the enzyme in the target cell membrane that converts thyroxine (T4) to its most potent form, triodothyronine (T3)
5’ monodeiodinase
It’s the precursor protein (molecule) for all thyroid hormones
Thyroglobulin
It is inactivated by phosphodiesterase
cAMP (cyclic AMP)
It’s the precursor for all steroid hormone
Cholesterol
Its synthesizes that releases melatonin
Pineal gland
This class of hormones bind to receptors on the cell membrane
Protein or peptide hormones
This pituitary hormone stimulates the liver to release insulin like growth factor - 1 (IGF-1)potentiating its effects throughout the entire body
GH
It is the main pituitary regulator of cortisol synthesis and secretion
ACTH (adrenocorticotropic hormone)
This pituitary hormone stimulates all aspects of thyroid function
TSH (thyroid stimulate hormone)
These two closely related neuropeptides are both stored and released by posterior pituitary gland
Oxytocin and vasopressin (ADH)
This hypothalamic nucleus is the major source of oxytocin
Paraventricular nucleus
Produces milk letdown, stimulates uterine contraction, promotes bonding
Oxytocin
This hypothalamic biogenic amine inhibits the release of prolactin from the anterior pituitary gland
Dopamine
This hypothalmic nucleus is the major source of vasopressin or ADH
Supraoptic nucleus
How are hypothalamic peptides preferentially control the anterior pituitary gland
Hypothalamo-hypophyseal portal system
It’s the enzyme in the target cell membrane that converts thyroxine (T4) to its most potent form, triodothyronine (T3)
5’ monodeiodinase
It’s the element that takes up 1/2 the molecular weight of thyroid hormones
Iodine
This form of T3 is inactive and may contribute to hypothyroidism
rT3 (reverse T3) (3,3’,5’- triiodothyronine)
Autoimmune disease where antibodies forma against TSH receptors causing form of hyperthyroidism goiter
Graves disease
This major mineralocorticoid control ECF volume and is regulated primarily by angiotensin II
Aldosterone
This enzyme deficiency is characterized by a deficiency of aldosterone, cortisol, 11-deoxycorocoserone and an elevation of 17-keotsteroids in the urine
21beta-hydroxylase deficiency
These 4 hormones are counter-regulatory to insulin in that they can raise blood glucose and offset insulin’s hypoglycemia effect
- Glucagon
- Epi
- Cortisol
- GH
