Jaundice Flashcards

1
Q

Important history for a baby with jaundice (10)

A

Term or preterm, type of delivery, risk factors for sepsis, maternal blood group, breast vs formula fed, volume and frequency of feeds, waking for feeds, wet nappies/stool, when was it noticed and have they already required treatment

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2
Q

Assessment of a jaundiced baby

A

Weight compared to birth, observations, alert or lethargic, top to toe check, abdomen for masses and stool colour

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3
Q

What is acceptable weight loss after birth

A

10% for formula fed and 12.5% for breast fed

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4
Q

When should a child be back to birth weight

A

By 3 weeks of age

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5
Q

What is jaundice

A

Yellowing of skin and sclera due to high levels of bilirubin in the blood

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6
Q

Cause of physiological jaundice

A

High concentrations of RBCs in the foetus and neonate which are more fragile than normal and less developed liver function - lots of bilirubin released which was normally excreted by placenta

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7
Q

What is physiological jaundice

A

Normal rise of bilirubin shortly after birth causing mild yellowing - usually resolves by 10 days

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8
Q

Causes of increased production of bilirubin (8)

A

Haemolytic disease of newborn, ABO incompatibility, haemorrhage, cepalo-haematoma, polycythaemia, sepsis and DIC, G6PD def

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9
Q

Causes of decreased clearance of bilirubin

A

Prematurity, breast milk jaundice, neonatal cholestasis, extrahepatic biliary atresia, hypothyroid and hypopituitary, Gilbert syndrome

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10
Q

When is jaundice pathological

A

IF present within first 24 hours of life

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11
Q

What causes premature jaundice

A

Exaggerated due to immature liver, increases risk of complications

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12
Q

What is Kernicterus

A

Brain damage due to high bilirubin levels

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13
Q

What is breast milk jaundice

A

Babies that are breastfed are more likely to have neonatal jaundice as breast milk inhibits the ability of the liver to process the bilirubin

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14
Q

What is haemolytic disease of the newborn

A

Cause of haemolysis and jaundice of newborn. By incompatibility between the rhesus antigen on the surface of RBCs of the mother and fetus

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15
Q

How long is prolonged jaundice

A

More than 14 days in term babies and more than 21 days in preterm babies

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16
Q

Causes of prolonged jaundice (3)

A

Biliary atresia, hypothyroidism and G6PD deficiency

17
Q

Management of jaundice

A

Phototherapy if above treatment line, and if extremely high then an exchange transfusion