Jaber - DKA and HHS Flashcards

1
Q
All of the following are signs of DKA except:
A. Hypotension
B. Dehydration
C. Bradycardia
D. Weight loss
E. Impaired consciousness and/or coma
A

C. Bradycardia (should be tachycardia)

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2
Q

In DKA, serum ketones will be _____.
A. Positive
B. Negative

A

A. Positive

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3
Q

In DKA, urine ketones will be _____.
A. Positive
B. Negative

A

A. Positive

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4
Q

In DKA, the serum glucose will be > _____.

A

250

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5
Q

In the treatment of DKA, you give IV fluids and regular insulin. At what rate is the insulin given?

A
  • 0.14 units/kg/hr as continuous infusion.
  • If serum glucose doesn’t fall by 10% in first hour, give 0.14 unit/kg bolus, then continue previous infusion.
  • when serum glucose reaches 200 mg/dL, reduce insulin infusion to 0.02-0.05 units/kg/hour or give rapid acting insulin at 0.1 units/kg SQ every 2 hours.
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6
Q

In the treatment of DKA, you give IV fluids and regular insulin. At what rate are fluids given?

A

Normal saline at 15-20 mL/kg/hour or 1-1.5 L/hour for first hour, then subsequent fluid replacement depends on patient specific factors.

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7
Q

For mild DKA, the anion gap will be > ____, while for moderate and severe DKA, the anion gap will be > ___.

A

Mild = >10

Moderate - severe = >12

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8
Q

What is the equation to calculate anion gap?

A

Anion gap = Na - (Cl + HCO3)

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9
Q

What is the equation for corrected serum Na?

A

Corrected Serum Na = Na + (1.6 (glucose - 100)/100)

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10
Q

In DKA, arterial pH will be less than or equal to ____.

A

7.3

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11
Q

When the pH is < ____, 100 mmol of bicarbonate must be given in 400 ml of water + 20 mEq KCl, infused for 2 hours and repeated every 2 hours until pH is greater than or equal to ____. Monitor K every __ hours.

A

6.9
7.0
Every 2 hours

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12
Q

In DKA, if potassium is < ____, hold insulin and give 20-30 mEq/hour of potassium until it is above that number.

A

3.3

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13
Q

In DKA, if potassium levels are between 3.3 and 5.2, what is the protocol?

A

Give 20-30 mEq K in each liter of IV fluids to keep serum potassium between 4-5 mEq/L.

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14
Q

In DKA, if K levels are > 5.2, what is the protocol?

A

Don’t give K, but check serum K levels every 2 hours.

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15
Q

In DKA, serum glucose should be kept between _____ and _____ until resolution of DKA.

A

150-200

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16
Q

Hyperosmolar hyperglycemic state (HHS) occurs in this patient population.

A

Type 2 diabetics and elderly patients with type 1 diabetes.

17
Q

True or False: mortality rate is higher for HHS than DKA.

18
Q

True or False: the management of DKA and HHS are similar.

19
Q

DKA is more common in type ___ diabetics.

20
Q

True or False: the hyperglycemia seen with DKA is more severe than that seen with HHS.

A

False: hyperglycemia is usually more severe with HHS than DKA.

21
Q

True or False: the Knesset of hyperglycemia is quicker in DKA than HHS.

22
Q
Positive ketones in serum and urine are seen in:
A. DKA
B. HHS
C. Both
D. None of the above
23
Q

True or False: Common symptoms of DKA include nausea, vomiting, and abdominal pain.

24
Q
\_\_\_\_\_\_ is the most common cause of death in children and adolescents with type 1 diabetes.
A. Heart disease
B. DKA
C. HHS
D. None of the above
25
What is the equation for effective serum osmolality?
Effective serum osmolality = 2(Na) + (glucose/18)
26
In DKA, you have a _____ insulin deficiency and an increase in counterregulatory hormones. A. Absolute B. Relative
A. Absolute
27
``` Patients with HHS have ____ insulin deficiency, while patients with DKA have ____ insulin deficiency. A. Absolute, absolute B. Absolute, relative C. Relative, absolute D. Relative, relative ```
C. Relative, absolute
28
True or False: the most common precipitating factors for DKA and HHS are infection and inadequate insulin production.
True
29
What is the criteria for transitioning patients from IV insulin to SQ in DKA?
1. Blood glucose less than 200 2. pH > 7.2 3. Anion gap less than or equal to 12 4. Bicarbonate > 15 Must meet blood glucose requirement + 2/3 of the others