Ix and Se of drugs 2.B Flashcards

1
Q

SE and PK of Morpine

A

PK: glucordinated to M6G, liphphillic

SE: 
Resp depression
constipation
tolerance
pinpoint pupils
hypersensitivity reaction ( increased his)
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2
Q

SE Nalbuphine

A

Sedation
headache
sweat
dysphoria

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3
Q

SE NSAIDS

A
  • Impaired kidney
  • Ulcer
  • Decreased contraction of utrus
  • Allergy
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4
Q

SE Asprin

A
Ulcer
bleeding
hyperuricemia
kidney imp
Allergy
Resp alk, metabolic acidosis
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5
Q

SE + Ix of Strong anti-inflamatory agents

A

Ix: Acute gout, patent ductus, uterine relax,
SE: Cardiotoxic, nephro, hematologic disease

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6
Q

SE of ibuprofen, Naproxen, ketoprofen

A

Cartilage damage

Nephrotoxic

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7
Q

SE cyclophosphamide

A

Se: Hemmoragic cystitis, pulmonary fibrosis, alopecia
Th: MESNA

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8
Q

SE cyclosporin A

A
  • Nephro-, hepato toxiv
  • Hyperglycemia, HTN, Hirtuism
  • Gingival hyperplasia, peripheral neuropathy
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9
Q

Cytokine SE

A
  • Hyperglycemia, Hyperlipid
  • BM supression
  • RTI
  • Gi disturbance
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10
Q

Se chemo

A
  • Nause
  • Anorexia
  • BM supression
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11
Q

Se cisplatin

A
  • Nephrotoxic (lethal)

- Cardiotoxic

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12
Q

SE bleomycin

A

Pulmonary fibrosis

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