IV anesthetics

Question 1

Induction dose of sodium thiopental

Answer 1

3-6mg/kg IV

Question 2

induction dose of ketamine

Answer 2

1-2mg/kg IV

Question 3

induction dose of etomidate

Answer 3

0.2-0.5mg/kg IV

Question 4

induction bolus dose of propofol

Answer 4

1-2.5mg/kg IV bolus

Question 5

induction infusion dose of propfol

Answer 5

50-200mcg/kg/min

Question 6

best induction agent for hypovolemic trauma pts?

Answer 6

ketamine, as long is there is no risk of increased ICP

Question 7

best induction agent for pts with asthma?

Answer 7

ketamine

Question 8

which IV induction agent is least likely to induce n/v?

Answer 8

propofol

Question 9

propofol’s CV effects

Answer 9

decrease in MAP due to combination of arterial and venous vasodilation. inhibition of baroreceoptor response - no reflex tachycardia

Question 10

respiratory effect of ketamine

Answer 10

bronchodilation

preserved respiratory drive

Question 11

CV effect of etomidate

Answer 11

relatively stable hemodynamic properties.

Question 12

describe presentation of propofol infusion syndrome

Answer 12

new onset metabolic acidosis, cardiac dysfunction, rhabdomyolysis, renal failure, hypertriglyceridemia
–thought to be secondary to impairment of mitochondrial oxidative phosphorylation and free fatty acid utilization leading to lactic acidosis and myocyte necrosis.