Itchy Skin Flashcards

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1
Q

When thinking about an itchy rash, what must we enquire about?

A

What came first; the itch or the rash?

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2
Q

If itching is present before a rash appears, what might this suggest?

A

This points more towards a systemic, neuropathic or psychogenic cause rather than a dermatological one

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3
Q

Define ‘Pruritus’

A

Itching without a rash

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4
Q

Define ‘Prurigo’

A

Intensely itchy papules and nodules

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5
Q

Define ‘Chronic Pruritus’

A

Itching that lasts >6weeks

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6
Q

What can be the consequence of chronic pruritus?

A
  • Excoriations
  • Lichenification
  • Hyperpigmentation
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7
Q

What Neurological conditions can cause a widespread itch?

A
  • Peripheral neuropathy
  • Post-herpetic neuropathy
  • Multiple sclerosis (MS)
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8
Q

What Metabolic causes can cause widespread itch?

A
  • Hyperthyroidism
  • Chronic Kidney Disease (CKD)
    + Secondary hyperparathyroidism
    + Uraemic pruritus
  • Diabetes
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9
Q

What Psychogenic conditions can cause widespread itch?

A
  • Parasitophobia
  • OCD
  • Depression/anxiety
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10
Q

What GI causes can lead to widespread itch?

A
  • Cholestasis
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11
Q

What malignant causes can lead to widespread itch?

A
  • Hodgkin’s lymphoma
  • Myeloid and lymphatic leukaemia
  • Solid malignant tumours (leading to paraneoplastic manifestation)
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12
Q

What haematological causes can lead to widespread rash?

A
  • Polycythaemia rubra vera

- Myeloid dysplasia

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13
Q

What inflammatory causes can lead to widespread rash?

A
  • Dermatomyositis

- Scleroderma

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14
Q

What infectious causes can lead to widespread rash?

A
  • HIV

- Hepatitis C

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15
Q

What is an iatrogenic cause for widespread itch?

A

Many drugs can cause skin itching

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16
Q

If faced with deranged LFTs, what is the first imaging investigation to arrange?

A

Liver USS