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Therapeutics III > Ischemic Heart Disease Lab Formulary > Flashcards

Ischemic Heart Disease Lab Formulary Flashcards

1
Q

Alteplase

A

t-PA, Activase

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2
Q

Alteplase (side effects)

A

Hemorrage

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3
Q

Alteplase (monitoring)

A

signs of bleeding, reduction in chest pain

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4
Q

Alteplase (dosing)

A

If >67kg: 15mg bolus followed by 50mg infusion over 30 minutes, then 35mg over 60 minutes
If <67kg: 15mg bolus, then 0.75mg/kg over 30 minutes, then 0.5mg/kg over 60 minutes

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5
Q

Captopril

A

Capoten

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6
Q

Captopril (side effects)

A

Hypotension, hyperkalemia, cough

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7
Q

Captopril (monitoring)

A

liver function, kidney function

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8
Q

Carvedilol

A

Coreg

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9
Q

Carvedilol (side effects)

A

Decreased HR, Decreased BP, hyperglycemia, peripheral edema

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10
Q

Carvedilol (monitoring)

A

reduction in angina

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11
Q

Carvedilol (dose)

A

25-50mg bid

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12
Q

Eplerenone

A

Inspra

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13
Q

Eplerenone (side effects)

A

Hyperkalemia, increased SCr

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14
Q

Eplerenone (monitoring)

A

Serum potassium

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15
Q

Eplerenone (dose)

A

50mg daily

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16
Q

Isosorbide mononitrate

A

Ismo, Imdur

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17
Q

Isosorbide mononitrate (side effects)

A

hypotension, dizziness, headache

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18
Q

Isosorbide mononitrate (monitoring)

A

reduciton in angina

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19
Q

Isosobide dinitrate

A

Isordil

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20
Q

Isosobide dinitrate (side effects)

A

hypotension, lightheadedness, headache

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21
Q

Isosobride dinitrate (monitoring)

A

reduction in angina

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22
Q

Nadolol

A

Corgard

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23
Q

Nadalol (side effects)

A

bradyarrhythmia, dizziness, fatigue

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24
Q

Nadalol (monitoring)

A

HR, reduction in angina

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25
Q

Nicardipine

A

Cardene

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26
Q

Nicardipene (side effects)

A

Hypotension, peripheral edema, tachyarrhythmia, N/V, headache

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27
Q

Nicardipene (monitoring)

A

reduction in angina

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28
Q

Nicardipene (dose)

A

20-40mg tid

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29
Q

Nifedipine

A

Adalat

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30
Q

Nifedipine (side effects)

A

Hypotension, palpitations, peripheral edema, flushing, nausea, dizziness, headache

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31
Q

Nifedipine (monitoring)

A

signs of chest pain

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32
Q

Nifedipine (dose)

A

10-30mg 3-4x/day, max 180mg/day

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33
Q

Nitroglycerin

A

Minitran, NitroDur, Nitrostat

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34
Q

Nitroglycerin (side effects)

A

Hypotension, flushing, dizziness

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35
Q

Nitroglycerin (monitoring)

A

relief of symptoms

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36
Q

Nitroglycerin (dosing)

A

(SL tablets) 1 tablet SL at first sign of attack; repeat every 5 minutes if needed for a total of 3 tablets in 15 minutes; if no relief, seek medical attention promptly
(ER Tabs) 2.5-6.5mg 3-4x/day
(Ointment) 7.5-30mg qam and 6 hrs after
(Patch) 0.2-0.8mg/hr

37
Q

Propranolol

38
Q

Propranolol (side effects)

A

diarrhea, vomiting, dizziness, fatigue

39
Q

Propranolol (monitoring)

A

HR, reduction in angina

40
Q

Propranolol (dose)

A

IR: 80-320mg/day (2-4x/day)
ER: 80mg qd up to 320mg max

41
Q

Ranolazine

42
Q

Ranolazine (side effects)

A

constipation, nausea, dizziness, headache

43
Q

Ranolazine (monitoring)

A

reduction of angina, sCr

44
Q

Ranolazine (dose)

A

500mg bid, increase to 1000mg bid

45
Q

Reteplase

46
Q

Reteplase (side effects)

A

hemorrhage

47
Q

Reteplase (monitoring)

A

Evidence of cardiac reperfusion, signs of bleeding

48
Q

Tenecteplase

49
Q

Tenecteplase (side effects)

A

hemorrhage

50
Q

Tenecteplase (monitoring)

A

ECG, cardiac enzymes, signs of bleeding

51
Q

Tenecteplase (dose)

A 
IV bolus
<60kg: 30mg
60-69kg: 35mg
70-79kg: 40mg
80-89kg: 45mg
>90kg: 50mg
52
Q

Ticagrelor

53
Q

Ticagrelor (side effects)

A

hemorrage, increased sCr, dyspnea

54
Q

Ticagrelor (monitoring)

A

reduction of CV events in pts w/ ACS

55
Q

Ticagrelor (dose)

A

180mg loading dose, then 90mg bid for 12 months

56
Q

Abciximab

57
Q

Abciximab (side effects)

A

chest pain, hypotension, nausea, hemorrhage, backache

58
Q

Abciximab (monitoring)

A

aPTT, platelet count

59
Q

Amlodipine

60
Q

Amlodipine (side effects)

A

peripheral edema, flushing, palpitations

61
Q

Amlodipine (monitoring)

A

reduction in angina

62
Q

atenolol

63
Q

atenolol (side effects)

A

Bradyarrhythmia, cold extremities, hypotension, dizziness, depression, fatigue

64
Q

atenolol (monitoring)

A

reduction in angina

65
Q

clopidogrel

66
Q

Clopidogrel (side effects)

A

hemorrhage

67
Q

Clopidogrel (monitoring)

A

signs of bleeding

68
Q

Clopidogrel (dose)

A

600mg at time of PCI, then 75mg daily

69
Q

eptifibatide

A

Integrelin

70
Q

eptifibatide (side effects)

A

hypotension, hemorrhage

71
Q

eptifibatide (monitoring)

A

PT, aPTT, ACT

72
Q

lisinopril

A

Prinvil, Zestril

73
Q

Lisinopril (side effects)

A

dry cough, chest pain, hypotension, headache

74
Q

Lisinopril (monitoring)

A

sCr, serum potassium

75
Q

Metoprolol

A

Lopressor, Toprol, Toprol XL

76
Q

Metoprolol (side effects)

A

bradyarrhythmia, dizziness, fatigue

77
Q

Metoprolol (monitoring)

A

reduction in angina, improved exercise tolerance

78
Q

Metoprolol (dose)

A

25-50mg q6 hrs (around 200mg/day for ER form)

79
Q

Prasugrel

80
Q

Prasugrel (side effects)

A

HTN, HLD, bachache, nosebleeds, headache

81
Q

Prasugrel (monitoring)

A

none listed

82
Q

Prasugrel (dose)

A

60mg loading dose, then 10mg daily

83
Q

Verapamil

A

Isoptin, Calan, Covera, Verelan

84
Q

Verapamil (side effects)

A

edema, headache, CONSTIPATION

85
Q

Verapamil (monitoring)

A

reduction in angina

86
Q

Verapamil (dose)

A

80-120mg tid

180mg daily for ER

87
Q

Tirofiban

88
Q

Tirofiban (side effects)

A

hemorrhage

89
Q

Tirofiban (monitoring)

A

Platelet count 6 hours after initiation and daily during therapy

Therapeutics III (11 decks)

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