Ischemic Heart Disease Flashcards
WHAT TYPE OF ANGINA PECTORIS
Occurs due to EXERTION (DEMAND problem)
STABLE or TYPICAL angina (most common)
WHAT TYPE OF ANGINA PECTORIS
Secondary to coronary artery SPASM
PRINZMETAL
WHAT TYPE OF ANGINA PECTORIS
May happen even at REST
SUPPLY problem
UNSTABLE (crescendo)
**PATTERNS OF MI: Transmural, Subendocardial or Multifocal microinfarction
REGIONAL: acute plaque change —> blood flow restored
CIRCUMFERENTIAL pattern: (+) SHOCK
SUBENDOCARDIAL
**PATTERNS OF MI: Transmural, Subendocardial or Multifocal microinfarction
Microembolization, vasculitis, vascular spasm
MULTIFOCAL MICROINFARCTION
**PATTERNS OF MI: Transmural, Subendocardial or Multifocal microinfarction
Epicardial vessel occlusion (NO intervention)
TRANSMURAL
Most common vessel involved in MI
LEFT ANTERIOR DESCENDING ARTERY (LAD)
When triphenyltetrazolium chloride is applied on fresh cardiac tissue, if the myocardium is VIABLE, what is the color?
BRICK-RED (indicating LDH activity)
When triphenyltetrazolium chloride is applied on fresh cardiac tissue, if the myocardium is NECTROTIC, what is the color?
PALE
MICROSCOPIC MORPHOLOGY of MI
6-12 HRS
COAGULATIVE NECROSIS
MICROSCOPIC MORPHOLOGY of MI
1-3 DAYS
ACUTE INFLAMMATION
MICROSCOPIC MORPHOLOGY of MI
3-7 DAYS
MACROPHAGES
MICROSCOPIC MORPHOLOGY of MI
7-10 DAYS
GRANULATION TISSUE
Cardiac marker that is used to assess REINFARCTION
CK-MB
~~ Because its level persist at a SHORTER duration (return to normal at 2-3 days)