ISCHEMIC BOWEL Flashcards
what is colonic ischemia?
mesenteric ischemia of colon leads to inflammation and sloughing of the intestinal mucosa
where is the most common area to see colonic ischemia?
splenic flexture and rectosigmoid junction (watershed areas)
what are the RF for colonic ischemia?
- > 60 F
- ASCVD
- CHF
- recent AAA surgery
- hx constipation
- hx HTN RX (esp vasoconstrictive)
what is the presentation of colonic ischemia?
- LLQ pain
- hematochezia (bloody diarrhea): typically self limited
what will you see on PE of colonic ischemia?
- LLQ tenderness- watch for peritoneal signs/fever (usually absent)
- absent/hypoactive bowel signs
what is the workup of colonic ischemia?
- CTA or MRA: intestinal ischemia; bowel wall edema; “thumb-printing”: segmental bowel wall thickening
- colonoscopy: ischemic changes to mucosa (GOLD STANDARD), edematous/friable tissue, can bx.
will you perfrom colonoscopy in suspected bowel perf or with peritoneal signs?
DO NOTTTT; pushing air up will make them sicker
What is the tx of colonic ischemia?
- IV fluids
- stable BP- avoid further hypotension/low flow state
- will usually resolve with supportive care - consider empiric broad spectrum abx
- coverage of gram neg and anaerobes
what is acute mesenteric ischemia?
inadequate perfusion through mesenteric vessels (embolic, low flow state) can lead to gangrene of bowel
fatal w/o intervention
what are the RF for acute mesenteric ischemia?
a fib
ascvd
recent MI
valvular dz
elderly
abd malignancy
hypercoagulability
paradoxical venous embolism -> shunt
what is the presentation of acute mesenteric ischemia?
- ACUTE SEVERE ABD PAIN w/ unremarkable PE
- N/V +/- GIB
- if have chronic ischemia may have postprandial abd pain, “food fear” and wt loss
what will you see on PE of acute mesenteric ischemia?
+/- peritoneal signs if perforation
what is the work up of acute mesenteric ischemia?
- leukocytosis, elevated lactate (depending on stage of dz), lactic acidosis
- abd CT often unremarkable (can help r/o perf, diverticulitis, obstruction, appendicitis, abscess)
- CTA IS GOLD STANDARD: NARROWING OF PROXIMAL VESSELS
- MRA: increase cost, time
what work up is the gold standard for acute mesenteric ischemia?
CTA IS GOLD STANDARD: NARROWING OF PROXIMAL VESSELS
what is the tx of acute mesenteric ischemia?
- restore flow w/ anticoag/thrombolysis if occlusive ischemia; angioplasty/stenting/bypass
- if bowel ischemia needs immediate exploratory surgery and if bowel viable poss bypass