Irritable Bowel Syndrome (IBS) Flashcards

1
Q

What are the 4 main parts of the colon?

A
  1. Ascending colon
  2. Transverse colon
  3. Descending colon
  4. Sigmoid colon
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2
Q

What are the main functions of the large intestine (colon)?

A
  1. Complete absorption from small intestines
  2. Manufactures vitamins, e.g. B/K
  3. Forms/expels faeces
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3
Q

Who is more prone to having IBS?

A
  1. Females
  2. Young people
  3. Those with family history
  4. Mental health
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4
Q

What is IBS classed as?

A

A functional, relapsing disorder (not a disease)

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5
Q

What are the symptoms of IBS?

A
  1. Cramping
  2. Diarrhoea
  3. Constipation
  4. Bloating
  5. Anorexia
  6. Flatulence
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6
Q

What is between the longitudinal and circular muscles of the GI walls?
What does it aid in?

A

The nervous plexus. It aids in the contraction of the colon muscles towards the rectum

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7
Q

What causes IBS in the colon?

A
  1. Disrupted muscle movements in the colon = contents not moving correctly.
  2. Stress
  3. Allergies
  4. Sensory/motor disorders
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8
Q

Which part of the colon is mostly affected in IBS?

A

The descending colon.

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9
Q

Which neurotransmitter is the most common between the enteric nervous system (system between layers of GI walls), & CNS?

A

Serotonin

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10
Q

What movement is the law of gut based on?

A

The peristalsis reflex.

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11
Q

What are the different types of IBS?

A
  1. Constipation-predominant (IBS-C)
  2. Diarrhoea-predominant (IBS-D)
  3. IBS mixed type (IBS-M)
  4. IBS un-subtyped (IBS-U)
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12
Q

How long should symptoms be present for it to be classed as IBS?

A

At least 12 weeks.

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13
Q

What are the tests used to diagnose IBS?

A
  1. Flexible sigmoidoscopy
  2. Colonoscopy
  3. CT scan
  4. Lactose intolerance tests
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14
Q

What red flags should you look out for in an IBS patient?

A
  1. Anaemia
  2. Fever
  3. Rectal bleeding
  4. IBD
  5. > 50 years old
  6. Weight loss
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15
Q

What dietary modifications can be implemented in a patient with IBS?

A
  1. Avoiding trigger foods, e.g. legumes
  2. Increase fibre intake
  3. Having a low FODMAP diet (fermentable oligo di mono-saccharides & polyols) - short chained carbs which are poorly absorbed in the SI
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16
Q

What pharmacological treatment options are available for IBS?

A
  1. Antispasmodics
  2. Tricyclic antidepressants
  3. SSRIs
  • FOR IBS-C
    1. Laxatives
    2. Cl- channel blockers
    3. Serotonin agonists
  • FOR IBS-D
    1. Antibiotics
    2. Anti-motility agents
    4. Serotonin antagonists
17
Q

When are anti-spadmodics/anticholinergics taken in IBS?

A

Take 30minutes before eating.

18
Q

When are laxatives given?

A

For IBS-C

19
Q

When are anti-diarrheals given (e.g. loperamide)?

A

For IBS-D

20
Q

When are tricyclic antidepressants/SSRIs given?

A
  1. For those with severe or refractory pain

2. More common in IBS-D

21
Q

When are serotonergic agents given?

A
  1. For IBS-C

2. Short term treatment for women with IBS-C

22
Q

What psychological treatments can be done for IBS?

A
  1. Psychotherapy
  2. Cognitive behavioural therapy
  3. Hypnotherapy