Iron Flashcards
How is the body’s iron compartmentalised?
Available ‘active’ iron
Stored iron
Where is the body’s available iron found?
Haemoglobin
Myoglobin
Tissue iron
Serum iron
How is iron stored in the body?
Ferritin
Haemosiderin
What is ferritin?
A soluble molecule with an iron mineral core
What is haemosiderin?
An insoluble form of iron store
Do humans have a pathway for excretion of iron?
No
How is the concentration of iron regulated?
By absorbing enough to match the losses
How much iron enters and leaves the body in a day?
1-2mg
What are the two types of dietary iron sources?
Haem iron
Non-Haem iron
Which source of iron is better?
Haem iron
How much haem iron is needed/day in the diet?
10-15mg
What is the metabolic product of digested haem iron?
Fe²⁺ (ferrous)
What is the metabolic product of digested non-haem iron?
Fe³⁺ (ferric)
How is haem iron absorbed and converted to Fe²⁺?
Enters the enterocytes of the small intestine wall and iron is released as Fe