Iris Atrophy Flashcards
Describe secondary iris atrophies
What its mainly due to, what happens to the iris, what ocular disease it can lead to
- Can be localized or diffuse
- mainly due to aging, trauma, surgery or infections
- Area of stroma thinning and depigmentation
- leads to corneal pigment dusting, secondary glaucoma
Describe Iridocorneal-endothelial sydrome
unlateral/bilateral, progressive?, age onset, what is it?
- unilateral
- slowly progressive
- young to middle age
- abnormal corneal endothelial layer (movement of endothelial cells off the cornea onto the iris)
What are ocular signs and symptoms of iridocorneal-endothelial syndrome?
(What’s seen on the iris?)
- Glaucoma (clogged TM)
- Iris atrophy
- Peripheral anterior synechiae
- Iris nodules
- Corneal endothelial problems/edema
- Corectopia: distortion of pupil
- Pseudopolycoria: 1 or more pupillary openings
- Ectropian uvea
Describe essential/progressive iris atrophy
Unilateral?, gender and age group, signs and symptoms
- unilateral, low grade inflammation reaction
- over 1-3 year time period
- women 30’s
- severe stromal atrophy, iris holes
- peripheral anterior synchiae
- secondary glaucoma and corneal endothelial problems
Describe Chandler’s syndrome
(Most common of iris atrophy?, ocular signs, corneal sign, effect on vision, glaucoma?, corectopia?)
Note: Greater corneal changes & edema, but fewer iris abnormalities
- most common atrophy
- PAS with severe corneal changes
- “silver hammered appearance”
- blurred vision and halos, secondary to edema
- unilateral glaucoma
- moderate corectopia, stromal atrophy
Describe Iris Nevus (Cogan-Reese) Syndrome
iris atrophy?, appearance, melanoma?
- diffuse or multiple pigmented iris nodules/nevi
- moderate iris atrophy
- smudge or matted appearance
- difffuse iris melanoma
What is the treatment for Iridocorneal Endothelial (ICE) syndromes
(How to treat glaucoma and corneal edema)
- Topical aqueous suppressant to manage secondary glaucoma
- May need penetrating keratoplasty for corneal edema
Describe Iridoschisis
bilateral, age onset, signs, secondary to IOP?
- bilateral, 6th decade
- split iris stroma into two layers, with fibrils of the anterior layers floating in aqueous
- associated with angle closure glaucoma
- secondary to high IOP
You have a 30 year old woman that presents with an iris inflammation only in the left eye. A SLE reveals several iris holes and a peripheral anterior synecchia as well as corneal endothelial problems. You also take their IOP and measure 34 mmHg in that eye potentially indicative of glaucoma. What is the diagnosis?
A. Essential/Progressive Iris Atrophy
B. Chander’s Syndrome
C. Iris-Nevus (Cogan-Reese) Syndrome
A. Essential/Progressive Iris Atrophy
You have a patient that presents blurry vision and appearance of halos in their left eye and a distorted pupil (corectopia). A SLE reveals a peripheral anterior synecchia, corneal edema as well as a “silver hammered appearance” on their cornea. You also take their IOP and measure 34 mmHg in that eye potentially indicative of glaucoma. What is the diagnosis?
A. Essential/Progressive Iris Atrophy
B. Chander’s Syndrome
C. Iris-Nevus (Cogan-Reese) Syndrome
B. Chander’s Syndrome
You have a patient that presents with several pigmented iris nodules. A SLE reveals roughly half the iris has atrophied and appears smudged. You also note what appears to be a diffuse melanoma. What is the diagnosis?
A. Essential/Progressive Iris Atrophy
B. Chander’s Syndrome
C. Iris-Nevus (Cogan-Reese) Syndrome
C. Iris-Nevus (Cogan-Reese) Syndrome
Which is the most common form of iriocorneal-endothelial syndrome?
A. Essential/Progressive Iris Atrophy
B. Chander’s Syndrome
C. Iris-Nevus (Cogan-Reese) Syndrome
B. Chander’s Syndrome
