IR and Ramen Flashcards
Which of the following is a key application of IR spectroscopy in pharmaceuticals?
A) Measuring radioactivity
B) Identifying molecular vibrations
C) Determining atomic structure
D) Measuring pH levels
B
What is the main advantage of Fourier Transform (FT) IR over dispersive IR?
A) Lower cost
B) Faster data acquisition
C) Higher resolution
D) Simpler sample preparation
B
Which functional group typically shows a strong absorption around 1700 cm⁻¹ in an IR spectrum?
A) Alcohol
B) Carboxylic acid
C) Amine
D) Alkane
B
In IR spectroscopy, what does the term ‘fingerprint region’ refer to?
A) The region where all molecules absorb
B) The region below 1200 cm⁻¹ unique to each molecule
C) The region above 3000 cm⁻¹
D) The region between 1500-2000 cm⁻¹
B
Which sample preparation method involves grinding the sample with KBr and pressing it into a disc?
A) Liquid film
B) Nujol mull
C) KBr disc
D) Diffuse reflectance
C
What is the primary purpose of the British Pharmacopoeia in relation to IR spectroscopy?
A) To set legal standards for drug quality
B) To develop new spectroscopy techniques
C) To provide medical diagnoses
D) To measure environmental pollutants
A
Which of the following modes of vibration involves a change in bond angle?
A) Symmetric stretch
B) Asymmetric stretch
C) Bending
D) Twisting
C
What is the typical wavenumber range for OH group absorption in IR spectroscopy?
A) 1600-1700 cm⁻¹
B) 2800-3000 cm⁻¹
C) 3200-3600 cm⁻¹
D) 4000-4500 cm⁻¹
C
Which type of IR spectroscopy instrument uses a Michelson interferometer?
A) Dispersive IR
B) FT-IR
C) UV-Vis
D) NMR
B
What is the main disadvantage of using water in IR spectroscopy?
A) It is too expensive
B) It masks hydroxyl group absorptions
C) It is not compatible with KBr discs
D) It causes fluorescence interference
B
What is the primary difference between Raman and IR spectroscopy?
A) Raman uses UV light, IR uses visible light
B) Raman measures scattered light, IR measures absorbed light
C) Raman is only used for solids, IR is only used for liquids
D) Raman is less expensive than IR
B
Which of the following is an advantage of Raman spectroscopy?
A) Strong signal intensity
B) Minimal sample preparation
C) Low cost
D) No interference from fluorescence
B
In Raman spectroscopy, what is Rayleigh scattering?
A) Scattering with no change in energy
B) Scattering with a decrease in energy
C) Scattering with an increase in energy
D) Scattering with a change in wavelength
A
Which component is essential for generating the Raman effect?
A) Monochromator
B) Laser source
C) KBr disc
D) Moving mirror
B
What type of samples can be analyzed using Raman spectroscopy?
A) Only solids
B) Only liquids
C) Aqueous samples
D) Only gases
Answer: C) Aqueous samples
C
