Iontophoresis Flashcards
Transcutaneous delivery of medications via application of direct electrical current
Iontophoresis
Iontophoresis is based on what principle?
“Like charges repel”
Iontophoresis most commonly used to apply
Dexamethasone
Approximate penetration?
1-2 cm
Indications for Iontophoresis
Analgesia Calcium deposits Fungal infection Hyperhidrosis Inflammation Ischemia Keloids Muscle spasm Myositis ossificans Plantar warts Scar tissue Wounds
Anode drives ____ ion
Cathode drives ____ ion
Positive +
Negative -
Transport of ion through skin is enhanced by
And dependent on
Imposed electric field
Ionic charge + weight
Electric repulsion of ions
Electromigration
ES increases porosity of superficial skin
Electroporation
Human skin has net (-) charge
Direction of ionic flow from…
Anode to cathode
3 mechanisms of iontophoresis
1) Repulsion of like charges
2) increase skin surface (pores)
3) electroosmosis
Movement of water and sodium toward cathode, creating stream where ions move
Electroosmosis
Pores in human skin are ____ charged.
Negatively
Routes of penetration through skin?
Sweat glands
oil glands
Hair follicles
Acidic and alkaline reactions can cause
Discomfort
Irritation
Burns