Iontophoresis

Question 1

Transcutaneous delivery of medications via application of direct electrical current

Answer 1

Iontophoresis

Question 2

Iontophoresis is based on what principle?

Answer 2

“Like charges repel”

Question 3

Iontophoresis most commonly used to apply

Answer 3

Dexamethasone

Question 4

Approximate penetration?

Answer 4

1-2 cm

Question 5

Indications for Iontophoresis

Answer 5

Analgesia
Calcium deposits
Fungal infection
Hyperhidrosis
Inflammation
Ischemia
Keloids
Muscle spasm
Myositis ossificans
Plantar warts
Scar tissue
Wounds

Question 6

Anode drives ____ ion

Cathode drives ____ ion

Answer 6

Positive +

Negative -

Question 7

Transport of ion through skin is enhanced by

And dependent on

Answer 7

Imposed electric field

Ionic charge + weight

Question 8

Electric repulsion of ions

Answer 8

Electromigration

Question 9

ES increases porosity of superficial skin

Answer 9

Electroporation

Question 10

Human skin has net (-) charge

Direction of ionic flow from…

Answer 10

Anode to cathode

Question 11

3 mechanisms of iontophoresis

Answer 11

1) Repulsion of like charges
2) increase skin surface (pores)
3) electroosmosis

Question 12

Movement of water and sodium toward cathode, creating stream where ions move

Answer 12

Electroosmosis

Question 13

Pores in human skin are ____ charged.

Answer 13

Negatively

Question 14

Routes of penetration through skin?

Answer 14

Sweat glands
oil glands
Hair follicles

Question 15

Acidic and alkaline reactions can cause

Answer 15

Discomfort
Irritation
Burns

Question 16

Dosage of Iontophoresis

Answer 16

40-80 mA/ minute

Question 17

For manufactured electrodes,

The size of electrode is___
And the pole is determined by

Answer 17

Fixed

Ion used

Question 18

Which electrodes are smaller?

Answer 18

Anode

Question 19

Active electrode goes over area of

Answer 19

Inflammation

Question 20

Cathode size :

Anode size:

Answer 20

.5

1

Question 21

Corticosteroid with anti-inflammatory effects

Answer 21

Dexamethasone

Question 22

Ions of dexamethasone have what polarity

Is it placed under anode or cathode

Answer 22

Negative

Cathode

Question 23

Anesthetic drug

Answer 23

Lidocaine

Question 24

Polarity and electrode of lidocaine

Answer 24

Positive

Anode

Question 25

Non-steroidal drug effective in reducing pain in lateral epicodylitis

Answer 25

Naproxen

Question 26

Synthetic opiate analgesic for post op pain,

Answer 26

Fentanyl

Question 27

Post-Tx considerations

Answer 27

Check for irritation Evaluate Tx and frequency, effectiveness

Question 28

Frequency of Iontophoresis dependent on

Answer 28

Ion selected Underlying condition

Question 29

Contraindications

Answer 29

``` Drug allergies Skin sensitivity Metal Tattoos Cuts ```

Question 30

Iontophoresis should not be applied after

Answer 30

Heat Ice US

Question 31

Difference between phonophoresis and Iontophoresis

Answer 31

P: US, Molecular transport, creme based, via process of calcification I: DC current, ion transport, liquid solution, repelling electric charge.