Ion channels and inhibitors Flashcards
1
Q
What is an inhibitor of Na+/K+-ATPase?
A
Ouabain
2
Q
What is an inhibitor of sodium channels?
A
TDX (tetradotoxin)
3
Q
What is an inhibitor of potassium channels?
A
TEA (tetraethylammonium)
4
Q
What are the effects of digitalis?
A
Blocks Na+/K+-ATPase in cardiac myocytes
5
Q
What are the inhibitors of ACh receptors?
A
- Curare
- α-bugarotoxin
6
Q
What are the inhibitors of ACh release?
A
- Tetanus toxin
- Botulinum toxin
7
Q
What are the inhibitors of AChE?
A
- Physostigmine
- Organophosphorus compounds (e.g. DFP)
8
Q
What is the function of latrotoxin?
A
Causes uncontrolled release of ACh from pre-synaptic terminals.
