Investigations of Allergy

Question 1

What are the 4 types of allergy testing?

Answer 1

Photographs and videos
SKIN PRICK TESTS ***
Blood tests - IgE
Patch testing - contact allergy

Question 2

Sensitivity and specificity difference?

Predictive values - what

Answer 2

Sensitive - very few false negatives

Specific - very few false positives

Likelihood for determining an outbreak or nonoutbreak of an infectious disease based on early warning results.

Question 3

IgE mediated disease - HELPFUL:

2 TESTS?

Non-IgE disease - UNHELPFUL”

What WCC can be measured in the blood? - 3

What may need to be biopsied for diagnosis?

What can be used to monitor nutrition in children?

Answer 3

Skin prick tests

Specific IgE blood test (ImmunoCap)

Eosinophils
Basophils
Mast cells

Gut, oesophagus, skin

Nutrition growth gentiles - malnutrition

Question 4

What does skin prick testing measure?

Answer 4

eThe measure of how allergic the patient is- may just be sensitised

Question 5

What are component resolved diagnostics?

Answer 5

Component-resolved diagnostics (CRD), also called component resolved diagnosis is a diagnostic approach that utilizes these purified native or recombinant allergens to detect the IgE antibodies response against the individual allergenic molecules

Question 6

Other tests:

What can be done for food allergies?

Answer 6

Food challenge - they ingest food and you wait for a reaction and have everything on standby

Challenge stopped if there is a reaction:

= If tolerates top dose = not allergic

= If reacts = allergic

= If unable to eat all doses = inconclusive