Investigations

Question 1

What does the pH of discharge indicate?

Answer 1

pH </= 4.5 - candidiasis
pH >/= 4.5 - bacterial vaginosis

Question 2

What test results would indicate premature ovarian failure?

Answer 2

• High FSH - measured twice with a month in between
• Raised FSH : LH
• Decreased oestradiol (<100pmol/l)

Question 3

What test results would indicate PCOS?

Answer 3

• LH/FSH - normal/high
• Prolactin - normal/high
• Testosterone - normal/high
• Impaired glucose tolerance

Question 4

What does the combined test for Down’s syndrome show?

Answer 4

• High Beta-HCG
• Low PAPPA-A
• Nuchal translucency

Question 5

What does the quadruple test for Down’s syndrome show?

Answer 5

• High Beta-HCG
• Low AFP
• High Inhibin A
• Low unconjugated oestriol (u53)

Question 6

When in pregnancy can you test for Down’s syndrome?

Answer 6

CVS - 9-12 weeks
Amniocentesis 15-19 weeks