Investigations

Question 1

24-h Urinary Free Cortisol Test

Answer 1

Cushing’s syndrome

Question 2

Overnight Dexamethasone Suppression test

Answer 2

Cushing’s Syndromes (Dexa is fake cortisol)

Question 3

Serum Corrected Calcium

Answer 3

Parathyroid Hormone test - Pathological fractures

Question 4

Short Synacthen Test

Answer 4

Addisons Disease (Low Aldosterone and Cortisol)

Question 5

Water Deprivation Test

Answer 5

Diabetes Insipidus

Question 6

Bloods show > 10 x ALT Increase and < 3x ALP Increase

Answer 6

Hepatocellular Injury

Question 7

Bloods show < 10 x ALT Increase and > 3x ALP Increase

Answer 7

Cholestasis

Question 8

Isolated raised ALP

Answer 8

Bone Mets or Vit D Deficiency

Question 9

Bilirubin raised, but ALT and ALP normal?

Answer 9

Haemolysis or Gilbert’s

Question 10

AMA Raised (Anti-mitochondial Antibodies)

Answer 10

Highly specific to PBC (Primary Biliary Cholangitis)

Question 11

ANA Raised (Anti-nuclear Antibodies)

Answer 11

Raised in SLE and most other autoimmune conditions like autoimmune hepatitis

Question 12

AST > ALT

Answer 12

Cirrhosis & Acute Alcoholic Hepatitis

Question 13

ALT > AST

Answer 13

Chronic Liver Disease