Introduction to physiology and homeostasis Flashcards

1
Q

What are control systems

A

-Mechanisms that exist within the human body to maintain homeostasis by monitoring key functions and variables
-Can be local or reflex

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2
Q

What is dynamic steady state

A

the internal environment is in a relatively steady state but is dynamic in that materials are constantly moving back and forth between extracellular and intracellular fluid
-Not the same as equilibrium but stable disequilibrium
-Aimed to maintain each respective compartment stable but not the same as each other

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3
Q

What are emergent properties

A

-Properties of a complex system that cannot be explained by a knowledge of a systems individual components
-greater than the simple sum of the system’s individual parts
-result from complex, nonlinear interaction of different components
-Emotion or intelligence cannot be predicted from knowing the individual properties of nerve cells

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4
Q

What is homeostasis

A

-Coined by Walter B. Cannon in 1929
-the ability to maintain a relatively stable internal environment (ECF) despite exposure to external variability (Blood pressure, body temp, ion/molecule concentration, gas partial pressures, etc.)

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5
Q

What is physiology

A

-The study of the normal functioning of all living organism and its components, parts, including all its chemical and physical processes
-Literally means “knowledge of nature”
-Key principles include homeostasis and regulation of the internal environment

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6
Q

What is a set point

A

the ideal value or range of values for a physiological parameter

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7
Q

What are all the levels of organization studied in physiology

A

-Molecules
-Cells
-Tissues
-Organs
-Organ systems
-Organisms
-Populations of one species

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8
Q

Name the 10 physiological organs of the body

A

-Circulatory
-Digestive
-Endocrine
-Immune
-Integumentary
-Muscoskeletal
-Nervous
-Reproductive
-Respiratory
-Urinary

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9
Q

What two systems are shown as a continuum rather than two distinct systems? Why?

A

-Nervous and endocrine systems
-Carry similar functions and have blurred as we have learned more about the integrative nature of physiological function

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10
Q

What are the two approaches when studying physiological processes? How do they differ?

A

Teleological (functional) approach:
-The ‘why’ or adaptive significance behind a system or event
-Explains why processes occur without elaborating on it’s function
The mechanistic approach:
-the ‘how’ of a system or process
-Provides concrete answer that explains exactly how a process works but does not explain the significance behind it

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11
Q

What is a pathological condition?

A

The result of a diseased state when the body fails to maintain homeostasis and normal function is disrupted

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12
Q

What are the two general groups of disease based on their origin?

A

Internal:
-Abnormal growth of cells (causing cancer or benign tumors)
-Production of antibodies against its own tissues (autoimmune diseases)
-The premature death of cells or the failure of cell processes
-Inherited disorders
External:
-Toxic chemicals
-Physical trauma
-Foreign invaders (bacteria and viruses)

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13
Q

What composes the body’s internal environment?

A

-Extracellular fluid (ECF): watery internal environment that surrounds the cell
-Serves as the transition between an organism’s external environment (Buffer zone)
-Intracellular fluid (ICF): Fluid inside cells

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14
Q

How does the ECF maintain homeostasis?

A

When ECF composition varies outside its normal range of values, compensatory mechanisms activate and try to return the fluid to the normal state

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15
Q

What is Mass Balance and why is it important to homeostasis?

A

-Law of Mass Balance: If the amount of substance in the body is to remain constant, any gain must be offset by an equal loss (Body’s load or ‘sodium load’)
-Maintains concentrations of substances such as oxygen, carbon dioxide, salts and hydroged ions (pH)
-Equation: Total amount of substance X in body = intake + production - excretion -metabolism

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16
Q

What are the two output options to maintain mass balance?

A

Excretion
-The elimination of material from the body, usually through the urine, feces, lungs or skin
-Many foreign substances that enter the body, such as drugs or artificial food additives (xenobiotics), are excreted by the liver and kidneys
Metabolism
-Converting the substance to a different substance through metabolism
-Nutrients that enter the body become the starting point for metabolic pathways that convert the original nutrient to a different molecule (Creates a new mass balance disturbance by adding a new metabolite)

17
Q

What is mass flow?

A

-Describes the rate of transport of a substance x as it moves through body fluids or into and out of the body
-Mass flow(amount x/min) = concentration of (x) x volume flow (amount of x/vol) x (vol/min)

18
Q

Describe local control

A

-Cells in close vicinity of the change initiate the response
-Includes Input signal, integrating center, output signal and a response

19
Q

Describe reflex control

A

-Uses long-distance signaling
-Is systemic and uses more complex control systems to maintain homeostasis through the nervous, endocrine system or both
-Broken into response loop and feedback loop
-Feedback loop modulates response loop and influences the input
-Can be antagonistic

20
Q

What are the 3 types of feedback loops and their functions?

A

Negative feedback loop:
-Homeostatic
-Response opposes or removes signal to stabilize system
-Can restore initial state but cannot prevent initial disturbance

Positive feedback loops:
-Not homeostatic
-Reinforce a stimulus to drive system away from normal value (childbirth)
-Requires intervention or outside event to cease response

Feedforward control:
-Anticipatory change that enables functions to prematurely begin

21
Q

What are biological rhythms and how do they change individuals set point?

A

-Set points vary from person to person or may vary over time
-Can be due to genetics or constant exposure to a new condition
-Biorhythms: variables that change predictably and create repeating patterns or cycles of changes (circadian rhythm)
-May create anticipatory response to predictable environment changes

22
Q

What are the seven steps in reflex control?

A

-Stimulus
-Sensor
-Input signal
-Integrating center
-Output signal
-Target
-Response