Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

CMED212 > Introduction To Perinatal Pharma > Flashcards

Introduction To Perinatal Pharma Flashcards

1
Q

Factors affecting drug pharmacokinetics in pregnancy

A 
Lipid solubility
Size and pH
Placental transporters
Protein binding
Placental and drug metabolism
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Factors that affect drug absorption in infants and children

A

Blood flow at the site of admin

Gastrointestinal function

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Increased oral absorption

A

Ampicilin and Pen G

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

The concentrations achieved in breastmilk are high enough so that signs of pyridoxine deficiency may occur in the infant if the mother is not given pyridoxine supplements

A

Isoniazid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Can cause thyroid suppression in infants and may increase the risk of subsequent thyroid cancer

A

Iodinated 125l albumin and radioiodine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Drugs that have side effects on lactation

A

Tetracycline, isoniazide, opioids, most sedatives and hypnotics,, lithium, iodinated 125l albumin and radioiodine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Exogenous surfactant; most effective within the first 30-60 mins of life

A

Beractant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Essential newborn care

A

Vitamin K1(phytonadione)
Hep B and BCG
Erythromycin 0.5%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Major risk factor for neonatal sepsis

A

Chorioamnionitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Most common pathogens responsible for early onset neonatal sepsis are

A

GBS

E.coli

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Antibiotic used for initial therapy

A

Ampicillin-gentamicin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Alternative to aminoglycoside

A

3rd gen cephalosporin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Contraindicated in neonates and may displace bilirubin leading to risk of kernicterus

A

Ceftriaxone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Drugs for neonatal sepsis

A 
Ampicilin-gentamicin
Penicillins
Ampicillin and amox
Cephalosphorin
Aminoglycosides
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Drug of choice for pCAP A or pCAP B

A

Amoxicillin trihydrate (40-50 mg/kg/day)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

More active against Mycobacterium avium complex and T. gondii

A

Azithromycin

17
Q

Is used in blood stream infections and endocarditis caused by methicilin-resistant staphylococci

A

IV vancomycin

18
Q

Used in pseudomembranous colitis by C.difficile

A

Oral vancomycin

19
Q

Cholera antibiotics

A 
Azithromycin
Doxycycline
Alternatives
Co-trimoxazole
Chloramphenicol
Erythromycin
20
Q

Shigella

A

Ceftriaxone

Ciprofloxacin

CMED212 (7 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions