introduction to DNA analysis week 4 Flashcards
(8 cards)
1
Q
what are the two types of DNA?
A
- nuclear DNA
- mitochondrial DNA
2
Q
3 factors of nuclear DNA
A
- one copy per cell
- located in nucleus
- contained within chromosomes
3
Q
3 characteristics of mitochondrial DNA
A
- maternally inherited only
- multiple copies in each cell
- circular genome
4
Q
what does DNA stand for?
A
deoxyribonucleic acid
5
Q
what is the structure of DNA?
A
a double helix of two complimentary strands having a phosphate sugar backbone with nitrogenous bases stacked inside.
6
Q
define an allele
A
an allele is a variant of the sequence of nucleotides at a particular location (locus) on a DNA molecule
7
Q
what are the 4 steps in isolation and purification of DNA?
A
- lyse
- bind
3.wash - elute
8
Q
define match probability
A
The probability that someone other than an unrelated to the nominated individual (victim, suspect) left the DNA and the match to this individual is entirely due to random chance
