Introduction to Dermoscopy Flashcards

1
Q

What is Dermoscopy?

A

Examination of the skin via skin microscopy with 10-14x magnification and a lighting system. Mainly used to evaluate pigmented lesions to distinguish malignant from benign.

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2
Q

In Dermoscopy, the pigmentation of lesions is evaluated by what 9 colours?

A

Black

Dark Brown

Tan

Grey

Steel Blue

Purple

White

Yellow

Red

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3
Q

How is symmetry described Clinically vs Dermatoscopically?

A

Clinically, symmetry is described in terms of shape of the lesion e.g. symmetrical vs asymmetrical.

Dermatoscopically, symmetry is described in terms of the pattern e.g. homogenous vs heterogenous colour and structure.

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4
Q

What are 4 types of borders which can be seen on benign and malignant naevi?

A

Irregular edge is often seen in melanoma, but is quite common in benign lesions too.

Fade out border-often seen in atypical naevi

Sharply demarcated in a small segment (typical of melanoma).

Sharp cut-off all the way around in a regular or irregular pattern.

A ‘moth-eaten’ edge is seen as concave areas at the edge of a lesion.

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5
Q

What is this lesion, and what are the white structures within it?

A

This lesion is a superficial BCC. Crystalline structures are shiny, bright white, parallel or disordered linear streaks. They are due to excessive collagen and may be seen in dermatofibroma, scar, BCC with fibroplasia, SCC, Spitz naevi and melanoma.

NB: White shiny areas are characterised by similar bright white structures of non-linear shape. Rosettes are four bright white points grouped together like a four-leaved clover, and are typical of actinic keratosis.

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6
Q

Describe the 3 point checklist in Dermoscopy, it’s purpose, and what each of the 3 points are:

A

The 3 point checklist has a high sensitivity for melanoma. There is a high liklihood of malignancy (melanoma/BCC) if a pigmented lesion has 2 of these criteria. It’s purpose is to inform non-experts on whether to perform a biopsy and thus not miss the detection of melanomas.

1-Asymmetry of colour and structure in one or two perpendicular axes

2-Atypical pigment network with irregular holes and thick lines

3-Blue-white structures: any type of blue or white colour, i.e. combination of blue-white veil and regression structure

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7
Q

Score this naevus based on the 3 point checklist

A

Reticular pattern-Naevua

Score=0

No asymmetry, no atypical network and no blue/white structures

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8
Q

Score this naevus based on the 3 point check list

A

Regular globules-Naevus

Score=1

Asymmetry, no atypical network and no blue/white structures

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9
Q

Score this naevus based on thie 3 point checklist:

A

Score =2

Asymmetry, A_typical network_ with no blue/white structures

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10
Q

Score this naevus based on the 3 point check list:

A

Score=3

Asymmetry, Atypical network and Blue/white structures

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11
Q

What is this lesion and does it have a typical pigment network?

A

Junctional Naevus

Typical pigment network

NB: Not all lesions with atypical network prove to be malignant.

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12
Q

What is this lesion and does it have a typical pigment network?

A

Plantar naevus

Typical pigment network

NB: Not all lesions with atypical network prove to be malignant.

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13
Q

What is this lesion and does it have a typical pigment network?

A

Facial Lentigo

Typical pigment network

NB: Not all lesions with atypical network prove to be malignant.

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14
Q

What is this lesion and does it have a typical pigment network?

A

Ephilis/Freckle

Typical pigment network

NB: Not all lesions with atypical network prove to be malignant.

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15
Q

What is this lesion and does it have a typical pigment network?

A

Compound Naevus

Typical pigment network

NB: Not all lesions with atypical network prove to be malignant.

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16
Q

What is this lesion and does it have a typical pigment network?

A

Junctional Naevus

Typical pigment network

NB: Not all lesions with atypical network prove to be malignant.

17
Q

What is this lesion and does it have a typical pigment network?

A

Melanoma

Atypical pigment network

Black arrows to broadened network, asterisk to streaming

NB: Not all lesions with atypical network prove to be malignant.

18
Q

What is this lesion and does it have a typical pigment network?

a) What is another name for this lesion, where does it most commonly present, describe the growth pattern and at what size does it become concerning?

A

Lentigo Maligna

Atypical pigment network

Black arrows to broadened network, asterisk to streaming

NB: Not all lesions with atypical network prove to be malignant.

a) Lentigo maligna is also known as Hutchinson melanotic freckle.
- It occurs in sun damaged skin so is generally found on the face or neck, particularly the nose and cheek.
- Lentigo maligna is an early form of melanoma in which the malignant cells are confined to the tissue of origin, the epidermis, hence it is often reported as ‘in situ’ melanoma.It grows slowly in diameter over 5 to 20 years or longer. Lentigo maligna melanoma is diagnosed when the melanoma cells have invaded into the dermis and deeper layers of skin. Lentigo maligna has a lower rate of transformation to invasive melanoma than the other forms of melanoma in situ (under 5% overall). However, the risk of invasive melanoma is greater in larger lesions, with up to 50% of those with diameter of greater than 4 cm being reported to have an invasive focus.

19
Q

What is this lesion and does it have a typical pigment network?

A

Lentigo Maligna

Atypical pigment network

Black arrows to broadened network, asterisk to streaming

NB: Not all lesions with atypical network prove to be malignant.

20
Q

What is this lesion and does it have a typical pigment network?

A

Melanoma

Atypical pigment network

Black arrows to broadened network, asterisk to streaming

NB: Not all lesions with atypical network prove to be malignant.

21
Q

What is this lesion and does it have a typical pigment network?

A

Lentigo Maligna

Atypical pigment network

Black arrows to broadened network, asterisk to streaming

NB: Not all lesions with atypical network prove to be malignant.

22
Q

What is this lesion and does it have a typical pigment network?

A

Lentigo Maligna/Melanoma in situ

Black arrows to broadened network, asterisk to streaming

NB: Not all lesions with atypical network prove to be malignant.

23
Q

What is this lesion and does it have a typical pigment network?

A

Lentigo Maligna

Atypical pigment network

Black arrows to broadened network, asterisk to streaming

NB: Not all lesions with atypical network prove to be malignant.

24
Q

What is this lesion and does it have a typical pigment network?

A

Lentigo Maligna

Atypical pigment network

Black arrows to broadened network, asterisk to streaming

NB: Not all lesions with atypical network prove to be malignant.

25
Q

What is this lesion and does it have a typical pigment network?

A

Atypical Naevus

Atypical pigment network

Black arrows to broadened network, asterisk to streaming

NB: Not all lesions with atypical network prove to be malignant.

26
Q

What is this lesion and does it have Blue/White structures?

If so, what does these structures mean?

A

Dysplastic Naevus

Contains a combination of blue-white veil and regression structures.

NB: The colour can be subtle. Not all lesions with blue-white structures are malignant.

27
Q

What is this lesion and does it have Blue/White structures?

A

Lentigo Maligna

Contains a combination of blue-white veil and regression structures.

NB: The colour can be subtle. Not all lesions with blue-white structures are malignant.

28
Q

What is this lesion and does it have Blue/White structures?

A

Melanoma

Contains a combination of blue-white veil and regression structures.

NB: The colour can be subtle. Not all lesions with blue-white structures are malignant.

29
Q

What is this lesion and does it have Blue/White structures?

A

Blue Naevus

Contains a combination of blue-white veil and regression structures.

NB: The colour can be subtle. Not all lesions with blue-white structures are malignant.

30
Q

What is this lesion and does it have Blue/White structures?

A

Congenital Naevus

Contains a combination of blue-white veil and regression structures.

NB: The colour can be subtle. Not all lesions with blue-white structures are malignant.

31
Q

What is this lesion and does it have Blue/White structures?

A

Basal Cell Carcinoma

Contains a combination of blue-white veil and regression structures.

NB: The colour can be subtle. Not all lesions with blue-white structures are malignant.

32
Q

What is this lesion and does it have Blue/White structures?

A

Dysplastic Naevus

Contains a combination of blue-white veil and regression structures.

NB: The colour can be subtle. Not all lesions with blue-white structures are malignant.

33
Q

What is this lesion and does it have Blue/White structures?

A

Melanoma

Contains a combination of blue-white veil and regression structures.

NB: The colour can be subtle. Not all lesions with blue-white structures are malignant.

34
Q

What is the first step algorithm for dermoscopy used for, and what are the 4 main steps?

A

First step algorithm for dermoscopy is used to distinguish melanocytic lesions from non-melanocytic lesions. It is used to evaluate pigmented lesions.

Steps:

1-Look for specific features of a melanocytic lesion.

2-If the above is absent, look for features to dx pigmented BCC, Seb K or haemangioma.

3-Consider whether the lesion could be a viral wart of dermatofibroma (look for central white patch).

4-If none of the above can be dx, treat as melanocytic.

35
Q

According to the international Dermoscopy society, how many benign histology reports should be received to every melanoma?

A

Dermatologists should aim to receive histology reports of 5-10 benign melanocytic lesions to every melanoma.

Less than that should prompt more excisions, more than 10 benign lesions to every melanoma should prompt more monitoring.

NB: There are inevitably differences in individual practices. Lesions may be removed for reasons not directly related to risk of malignancy (e.g. cosmetic reasons or to relieve anxiety).

36
Q
A