Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Dermoscopy > Dermatological Structures of Melanocytic Lesions > Flashcards

Dermatological Structures of Melanocytic Lesions Flashcards

1
Q

What 3 types of structure are melanocytic lesions made up of?

A

1-Pigment Network &/Or

2-Amorphous Strucureless Area (blotches) &/Or

3-Dots and Globules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the significance of these structures in Benign vs melanocytic lesions?

A

Benign lesions tend to have only 1 or 2 of these structures in a symmetrical distribution. Melanocytic lesions tend to have all 3 of these structures in a atypical distribution.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is a pigment network and what are the paler ‘holes’?

A

Pigment network is formed by melanocytes. Dense pigment rings (the grid) are due to projections of ridges. Paler ‘holes’ are due to projections of dermal papillae

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is a ‘Pseudonetwork’?

A

This term is used to describe the annular pigment seen around hair follicles on facial skin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is CHAOS and CLUES?

A

CHAOS looks for atypical or irregular pigment network including asymmetry of structure or colour.

CLUES are used to diagnose malignancy.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are the 10 CLUES to malignancy? (melanoma and nonmelanocytic naevus)

A

1-Thick reticular lines, often with irregular holes.

2-Radial Streaming (lines at the periphery, which often represent the radial growth phase of melanoma).

3-Pseudopods (bulbous projections at edge of lesion due to junctional nests of abnormal melanocytes in invasive melanoma)

4-Black dots in the periphery

5-Polymorphous vascular pattern

6-Parallel lines on ridges

7-Eccentric structureless area of colour

8-White lines

9-Large Polygons

10-Grey or Blue structures of any kind

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is a Negative Pigment Network and what is it caused by?

A

NPN refers to a white reticular pattern due to elongated rete pegs.

It is a characteristic of melanoma but can also be seen in Spitz naevi and dysplastic naevi. It may resemble the pattern seen in scars on the lower leg (atrophie blanche). It should not be confused with the pale colour separating the globules of a benign naevus.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are the 4 types of ‘Parallel Pattern’ network seen on palmar and plantar skin surfaces?

A

1-Parallel Furrow Pattern: Pigmented furrows

2-Lattice pattern: Pigmented furrows with lines crossing

3-Fibrillar/filamentous pattern: Delicate pigmentation crossing the skin markings

4-Parallel Ridge Pattern: Pigmented ridges (white dots represent sweat duct openings). This pattern is highly specific for melanoma in volar sites.

NB: There can be a Mixed pattern of lattice and parallel furrow.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is an Amorphous area and what are the two types? What is an important consideration about one of the types?

Which layer of the skin does a brown amorphous area arise?

A

Amorphous area means an area of pigmentation without specific structural features (blotch). The two types are diffuse and irregular.

  • Diffuse amorphous areas are most often benign e.g. solar lentigo, benign naevus or blue naevus.
  • Irregular amorphous areas may be the only dermatoscopic feature of melanoma.
  • Brown amorphous area may be due to pigment in the basal layer (or papillary dermis) and arise when the rete ridges are flattened out.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

1-What are dots and globules?

2-Which colour arises from what skin layer?

3-What are 5 different types of Dots and Globules depending on location and colour?

A

1-Globules are large dots. Dots and Globules represent localised pigment

2-Black dots are free melanin in the stratum corneum, Brown globules are due to junctional nests of melanocytes, and Blue or Grey dots are due to melanophages in the dermis.

3-

a) Central black dots and globules tend to be in Benign lesions
b) Circumferential brown globules are seen in some enlarging dysplastic naevi.
c) Uniform globules with squarish or angulated shape are referred to as cobblestone pattern.
d) Diffuse blue/grey dots in the absence of a pigment network are characteristic of lichenoid keratosis.
e) Tiny brown dots in clusters are characteristic of melanoma.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Benign and malignant melanocytic lesions may have what 5 characteristics:

A

1-Pigment network or pseudonetwork

2-Aggregated globules

3-Streaks

4-Homogeneous blue pigmentation
(also in haemangiomas, BCC and melanoma

mets)

5-Parallel pattern

NB: Or, NONE of the listed criteria

(also in solar lentigo, seb-k, actinic keratosis, dermatofibroma and accessory nipple)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What main melanocytic characteristic can be seen here?

A

Multiple melanocytic features

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What main melanocytic characteristic can be seen here?

A

Multiple melanocytic features

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What main melanocytic characteristic can be seen here?

A

Homogenous Blue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What main melanocytic characteristic can be seen here?

A

Streaks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What main melanocytic characteristic can be seen here?

A

No melanocytic criteria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What main melanocytic characteristic can be seen here?

A

Aggregated Globules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What main melanocytic characteristic can be seen here?

A

Paralell pattern

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What main melanocytic characteristic can be seen here?

A

Pseudonetwork

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What main melanocytic characteristic can be seen here?

A

Pigment network

21
Q

What are the 7 classification types of melanocytic naevi?

A

1-Globular (congential) naevus

2-Reticular (acquired) naevus

3-Starburst (spitz/Reed) naevus

4-Blue (homogenous) naevus

5-Site-related naevi (e.g. lips, face, nails, genitals, nipple)

6-Naevi with special features (6 types)

7-Unclassifiable melanocytic lesions

22
Q

What are the 6 types of ‘naevi with special features’?

A

1-Combined naevi (two types of naevi juxtaposed or merged)

2-Halo naevi (uniform lymphocytic reaction)

3-Irritated naevi (patchy lymphocytic reaction)

4-Cockade naevus

5-Naevi with eczematous halo (Meyerson type)

6-Recurrent naevi following surgery

23
Q

Name this melanocytic naevus

A

Unclassifiable melanocytic lesion

24
Q

Name this melanocytic naevus

A

Unclassifiable melanocytic lesion

25
Q

Name this melanocytic naevus

A

Naevi with special features (Recurrent naevi)

26
Q

Name this melanocytic naevus

A

Naevi with special features (Recurrent naevi)

27
Q

Name this melanocytic naevus

A

Naevi with special features (Recurrent naevi)

28
Q

Name this melanocytic naevus

A

Naevi with special features (Naevi with eczematous halo-meyerson type)

29
Q

Name this melanocytic naevus

A

Naevi with special features (Naevi with eczematous halo-meyerson type)

30
Q

Name this melanocytic naevus

A

Naevi with special features (cockade naevus)

31
Q

Name this melanocytic naevus

A

Naevi with special features (cockade naevus)

32
Q

Name this melanocytic naevus

A

Naevi with special features (halo naevus)

33
Q

Name this melanocytic naevus

A

Naevi with special features (halo naevus)

34
Q

Name this melanocytic naevus

A

Naevi with special features (combined naevus)

35
Q

Name this melanocytic naevus

A

Site related naevus (facial)

36
Q

Name this melanocytic naevus

A

Site related naevus (facial)

37
Q

Name this melanocytic naevus

A

Site related naevus (subungual)

38
Q

Name this melanocytic naevus

A

Site related naevus (acral)

39
Q

Name this melanocytic naevus

A

Blue naevus (clinical)

40
Q

Name this melanocytic naevus

A

Starburst (Spitz) naevus (clinical)

41
Q

Name this melanocytic naevus

A

Starburst (Spitz) naevus (dermatoscopic)

42
Q

Name this melanocytic naevus

A

Starburst (Spitz) naevus (dermatoscopic)

43
Q

Name this melanocytic naevus

A

Starburst (Spitz) naevus (clinical)

44
Q

Name this melanocytic naevus

A

Reticular pattern (dermoscopic)

45
Q

Name this melanocytic naevus

A

Reticular pattern (clinical)

46
Q

Name this melanocytic naevus

A

Globular Naevus-Fried egg pattern (clinical)

47
Q

Name this melanocytic naevus

A

Globular Naevus-Fried egg pattern (dermoscopy)

48
Q

Name this melanocytic naevus

A

Globular Naevus (dermoscopy)

49
Q

Name this melanocytic naevus

A

Globular Naevus (clinical)

Dermoscopy (12 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions